Opamtistomig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 13:30:45 GMT 2025` Edited by `admin` on `Wed Apr 02 13:30:45 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	K3DDY28BJF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Opamtistomig

Official Name

English

H-gamma1 heavy chain anti-CD274 fused to a scFvhl anti-TNFRSF9 (1-714) [H-gamma1 heavy chain anti-CD274 humanized (1-449) [VH (Homo sapiens IGHV4-30-4*09 (87.8%) -(IGHD) -IGHJ4*01 (93.3%) L123>T (114), CDRIMGT [8.7.13] (26-33.51-57.96-108)) (1-119)-Homo

Preferred Name

English

Immunoglobulin G1 [236-alanine,237-alanine,267-alanine,331-alanine], anti-(human/Macaca fascicularis programmed death-ligand PD-L1) (human-Mus musculus monoclonal HUL02 ?1-chain) fusion protein with peptide linker ((GGGGS)3) fusion protein with immunoglo

Common Name

English

opamtistomig [INN]

Common Name

English

immunoglobulin (H-gamma1-scFvhl_L-kappa) dimer, anti-[Homo sapiens CD274 (programmed cell death 1 ligand 1, PDL1, PD-L1, B7 homolog 1, B7H1, B7-H1, PDCD1LG1)] and anti-[Homo sapiens TNFRSF9 (TNF receptor superfamily member 9, 4-1BB, T cell antigen ILA, C

Common Name

English

Code System Code Type Description

FDA UNII

K3DDY28BJF

Created by admin on Wed Apr 02 13:30:45 GMT 2025 , Edited by admin on Wed Apr 02 13:30:45 GMT 2025

PRIMARY

CAS

2923499-76-5

Created by admin on Wed Apr 02 13:30:45 GMT 2025 , Edited by admin on Wed Apr 02 13:30:45 GMT 2025

PRIMARY

INN

13330

Created by admin on Wed Apr 02 13:30:45 GMT 2025 , Edited by admin on Wed Apr 02 13:30:45 GMT 2025

PRIMARY

From	To
1_231	2_231
1_228	2_228
2_222	4_214
1_222	3_214
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
1_625	1_693
2_625	2_693
1_508	1_707
2_508	2_707
1_486	1_560
2_486	2_560
1_369	1_427
2_369	2_427
1_263	1_323
2_263	2_323
1_146	1_202
2_146	2_202
1_22	1_95
2_22	2_95

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					7VWM3OLK0G

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9

TARGET -> AGONIST

Amount:

Related Record Type Details


					K3DDY28BJF

Opamtistomig

ACTIVE MOIETY

Interaction Type:

PRECLINICAL

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL