MANEB

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H6N2S4.Mn
Molecular Weight	265.302
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Mn++].[S-]C(=S)NCCNC([S-])=S

InChI

InChIKey=YKSNLCVSTHTHJA-UHFFFAOYSA-L

InChI=1S/C4H8N2S4.Mn/c7-3(8)5-1-2-6-4(9)10;/h1-2H2,(H2,5,7,8)(H2,6,9,10);/q;+2/p-2

HIDE SMILES / InChI

Molecular Formula	Mn
Molecular Weight	54.938
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C4H8N2S4
Molecular Weight	212.38
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Genotoxic and mono-oxygenase system effects of the fungicide maneb.	2000 Sep	11043497
Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype.	2003 Aug	12911755
Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: relevance to Parkinson's disease.	2004	15350641
Retinal degeneration and other eye disorders in wives of farmer pesticide applicators enrolled in the agricultural health study.	2005 Jun 1	15901622
[WITHDRAWN] Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype.	2005 Jun 10	15824117
Identification of differentially expressed proteins in striatum of maneb-and paraquat-induced Parkinson's disease phenotype in mouse.	2007 Sep-Oct	17532186
Pesticide use and thyroid disease among women in the Agricultural Health Study.	2010 Feb 15	20061368
Environmental impact on vascular development predicted by high-throughput screening.	2011 Nov	21788198
Paraquat, but not maneb, induces synucleinopathy and tauopathy in striata of mice through inhibition of proteasomal and autophagic pathways.	2012	22292029
Minocycline, levodopa and MnTMPyP induced changes in the mitochondrial proteome profile of MPTP and maneb and paraquat mice models of Parkinson's disease.	2013 Aug	23562983
Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays.	2013 Jun 17	23611293
Maneb causes pro-oxidant effects in the hippocampus of Nrf2 knockout mice.	2013 Sep	23764462
Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ-NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease.	2015 May-Jun	24376148

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:33:43 UTC 2023` Edited by `admin` on `Sat Dec 16 05:33:43 UTC 2023`
Record UNII	K221E12G7T
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MANEB

Common Name

English

1,2-ETHYLENEDIYLBIS(CARBAMODITHIOATO)MANGANESE

Common Name

English

ETHYLENEBIS(DITHIOCARBAMIC ACID) MANGANOUS SALT

Common Name

English

MANEB 80

Common Name

English

MANEBGAN

Common Name

English

MANEB [IARC]

Common Name

English

MANEB [ISO]

Common Name

English

CARBAMODITHIOIC ACID, 1,2-ETHANEDIYLBIS-, MANGANESE COMPLEX

Common Name

English

MANEB [MI]

Common Name

English

MANGANESE, (N-(2-((DITHIOCARBOXY)AMINO)ETHYL)CARBAMODITHIOATO(2-)-.KAPPA.S,.KAPPA.S')-

Common Name

English

MANGANESE, ((1,2-ETHANEDIYLBIS(CARBAMODITHIOATO))(2-))-

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

14505