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Details

Stereochemistry UNKNOWN
Molecular Formula C15H11ClO2
Molecular Weight 258.7
Optical Activity ( + )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLORIDAROL, (+)-

SMILES

OC(C1=CC2=C(O1)C=CC=C2)C3=CC=C(Cl)C=C3

InChI

InChIKey=KBFBRIPYVVGWRS-UHFFFAOYSA-N
InChI=1S/C15H11ClO2/c16-12-7-5-10(6-8-12)15(17)14-9-11-3-1-2-4-13(11)18-14/h1-9,15,17H

HIDE SMILES / InChI

Molecular Formula C15H11ClO2
Molecular Weight 258.7
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Cloridarol is a vasodilator that was studied for the treatment of coronary insufficiency in Italy in the 1970s. In normolipidemic rats, cloridarol decreased plasma triglycerides without affecting cholesterolemia and fast- or norepinephrine-induced lipolysis. The drug proved effective in reducing fructose-induced hypertriglyceridemia and dietary hypercholesterolemia in rats.

Approval Year

Sample Use Guides

In Vivo Use Guide
750 mg/day for at least 20 days
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Dec 16 18:37:21 GMT 2023
Edited
by admin
on Sat Dec 16 18:37:21 GMT 2023
Record UNII
JXI9IO55VI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CLORIDAROL, (+)-
Common Name English
2-BENZOFURANMETHANOL, .ALPHA.-(4-CHLOROPHENYL)-, (+)-
Systematic Name English
Code System Code Type Description
FDA UNII
JXI9IO55VI
Created by admin on Sat Dec 16 18:37:21 GMT 2023 , Edited by admin on Sat Dec 16 18:37:21 GMT 2023
PRIMARY
CAS
1290045-29-2
Created by admin on Sat Dec 16 18:37:21 GMT 2023 , Edited by admin on Sat Dec 16 18:37:21 GMT 2023
PRIMARY