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Details

Stereochemistry ABSOLUTE
Molecular Formula C28H49NO
Molecular Weight 415.6948
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MK-386

SMILES

[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](C)C[C@@]4([H])N(C)C(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C

InChI

InChIKey=XUTZDXHKQDPUMA-MVJJLJOTSA-N
InChI=1S/C28H49NO/c1-18(2)9-8-10-19(3)21-11-12-22-26-20(4)17-24-28(6,16-14-25(30)29(24)7)23(26)13-15-27(21,22)5/h18-24,26H,8-17H2,1-7H3/t19-,20+,21-,22+,23+,24-,26+,27-,28-/m1/s1

HIDE SMILES / InChI

Molecular Formula C28H49NO
Molecular Weight 415.6948
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 8 / 9
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
0.9 nM [IC50]
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:54:22 GMT 2023
Edited
by admin
on Fri Dec 15 15:54:22 GMT 2023
Record UNII
JWDKP12EUC
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MK-386
Code English
L-733692
Code English
2H-INDENO(5,4-F)QUINOLIN-2-ONE, 7-((1R)-1,5-DIMETHYLHEXYL)HEXADECAHYDRO-1,4A,6A,10-TETRAMETHYL-, (4AR,4BS,6AR,7R,9AS,9BS,10S,11AR)-
Common Name English
2H-INDENO(5,4-F)QUINOLIN-2-ONE, 7-(1,5-DIMETHYLHEXYL)HEXADECAHYDRO-1,4A,6A,10-TETRAMETHYL-, (4AR-(4A.ALPHA.,4B.BETA.,6A.ALPHA.,7.ALPHA.(R*),9A.BETA.,9B.ALPHA.,10.ALPHA.,11A.BETA.))-
Systematic Name English
4-AZACHOLESTAN-3-ONE, 4,7-DIMETHYL-, (5.ALPHA.,7.BETA.)-
Systematic Name English
Code System Code Type Description
PUBCHEM
9888107
Created by admin on Fri Dec 15 15:54:22 GMT 2023 , Edited by admin on Fri Dec 15 15:54:22 GMT 2023
PRIMARY
FDA UNII
JWDKP12EUC
Created by admin on Fri Dec 15 15:54:22 GMT 2023 , Edited by admin on Fri Dec 15 15:54:22 GMT 2023
PRIMARY
CAS
158493-17-5
Created by admin on Fri Dec 15 15:54:22 GMT 2023 , Edited by admin on Fri Dec 15 15:54:22 GMT 2023
PRIMARY
WIKIPEDIA
MK-386
Created by admin on Fri Dec 15 15:54:22 GMT 2023 , Edited by admin on Fri Dec 15 15:54:22 GMT 2023
PRIMARY
EPA CompTox
DTXSID20935926
Created by admin on Fri Dec 15 15:54:22 GMT 2023 , Edited by admin on Fri Dec 15 15:54:22 GMT 2023
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
IC50
TARGET->WEAK INHIBITOR
IC50
Related Record Type Details
ACTIVE MOIETY