MK-386

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C28H49NO
Molecular Weight	415.6948
Optical Activity	UNSPECIFIED
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](C)C[C@@]4([H])N(C)C(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C

InChI

InChIKey=XUTZDXHKQDPUMA-MVJJLJOTSA-N

InChI=1S/C28H49NO/c1-18(2)9-8-10-19(3)21-11-12-22-26-20(4)17-24-28(6,16-14-25(30)29(24)7)23(26)13-15-27(21,22)5/h18-24,26H,8-17H2,1-7H3/t19-,20+,21-,22+,23+,24-,26+,27-,28-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C28H49NO
Molecular Weight	415.6948
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	8 / 9
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Steroid 5-alpha-reductase 1 5 Target ID: CHEMBL1787 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7966146	Inhibitor 8297		0.9 nM [IC50]

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:54:22 UTC 2023` Edited by `admin` on `Fri Dec 15 15:54:22 UTC 2023`
Record UNII	JWDKP12EUC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MK-386

Code

English

L-733692

Code

English

2H-INDENO(5,4-F)QUINOLIN-2-ONE, 7-((1R)-1,5-DIMETHYLHEXYL)HEXADECAHYDRO-1,4A,6A,10-TETRAMETHYL-, (4AR,4BS,6AR,7R,9AS,9BS,10S,11AR)-

Common Name

English

2H-INDENO(5,4-F)QUINOLIN-2-ONE, 7-(1,5-DIMETHYLHEXYL)HEXADECAHYDRO-1,4A,6A,10-TETRAMETHYL-, (4AR-(4A.ALPHA.,4B.BETA.,6A.ALPHA.,7.ALPHA.(R*),9A.BETA.,9B.ALPHA.,10.ALPHA.,11A.BETA.))-

Systematic Name

English

4-AZACHOLESTAN-3-ONE, 4,7-DIMETHYL-, (5.ALPHA.,7.BETA.)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

9888107