Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 19:53:58 GMT 2023
by
admin
on
Sat Dec 16 19:53:58 GMT 2023
|
| Protein Type | PEPTIDE |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
JW7KCN7MMK
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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Q66K64
Created by
admin on Sat Dec 16 19:53:58 GMT 2023 , Edited by admin on Sat Dec 16 19:53:58 GMT 2023
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PRIMARY | |||
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JW7KCN7MMK
Created by
admin on Sat Dec 16 19:53:58 GMT 2023 , Edited by admin on Sat Dec 16 19:53:58 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
DEGRADER->TARGET |
Indisulam induces a ternary protein complex between RNA Binding Motif 39 (RBM39) and the E3 ubiquitin ligase receptor DDB1 and CUL4 associated factor 15 (DCAF15) resulting in rapid proteasomal degradation of RBM39, aberrant RNA splicing and cell death.
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Molecular Formula | CHEMICAL |
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| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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