| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H6O4S |
| Molecular Weight | 126.132 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COS(=O)(=O)OC
InChI
InChIKey=VAYGXNSJCAHWJZ-UHFFFAOYSA-N
InChI=1S/C2H6O4S/c1-5-7(3,4)6-2/h1-2H3
| Molecular Formula | C2H6O4S |
| Molecular Weight | 126.132 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Dimethyl sulfate is a diester of methanol and sulfuric acid. Dimethyl sulfate is commonly used as a reagent for the methylation of phenols, amines, and thiols. Dimethyl sulfate is a potent genotoxic chemical. It can directly alkylate DNA both in vitro and in vivo. It have been shown to induce mutations, chromosomal aberrations, and other genetic alterations in a diversity of organisms. Dimethyl sulfate can cause severe burns to the skin, eyes, and respiratory tract. Systemic effects of dimethyl sulfate include damage to the liver and kidneys.
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PubMed
Patents
Sample Use Guides
A single dose of dimethyl sulfate giving an initial concentration of 400 uM raised the levels of nuclear monomeric and polymeric (ADPribose) residues within 20 min to 12- and 21-fold higher values,
respectively, as compared to the low basal amounts detected in untreated control cells.