2-(2-CARBOXYETHYL)-4-METHYL-5-PROPYLFURAN-3-CARBOXYLICACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H16O5
Molecular Weight	240.2524
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 2-(2-CARBOXYETHYL)-4-METHYL-5-PROPYLFURAN-3-CARBOXYLICACID

Structure Search

SMILES

CCCC1=C(C)C(C(O)=O)=C(CCC(O)=O)O1

InChI

InChIKey=WMCQWXZMVIETAO-UHFFFAOYSA-N

InChI=1S/C12H16O5/c1-3-4-8-7(2)11(12(15)16)9(17-8)5-6-10(13)14/h3-6H2,1-2H3,(H,13,14)(H,15,16)

HIDE SMILES / InChI

Molecular Formula	C12H16O5
Molecular Weight	240.2524
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Solute carrier family 22 member 6 19 Target ID: CHEMBL1641347 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14675047	Substrate 661
Solute carrier family 22 member 8 17 Target ID: CHEMBL1641348 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14675047	Substrate 661

PubMed

Title	Date	PubMed
Behavior of non-protein-bound and protein-bound uremic solutes during daily hemodialysis.	2002 Aug	12148107
Renal disposition of a furan dicarboxylic acid and other uremic toxins in the rat.	2002 Nov	12388676
Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain.	2002 Oct	12358729
Protein-bound uremic retention solutes.	2003 Oct	14681860
Characterization of uremic toxin transport by organic anion transporters in the kidney.	2004 Jan	14675047
Effects of uremic toxins on hepatic uptake and metabolism of erythromycin.	2004 Nov	15286055
Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats.	2005 Apr	15846470
New approaches to the removal of protein-bound toxins from blood plasma of uremic patients.	2007	17573628
[Interpretations of laboratory test data on serum protein binding].	2007 Feb	17268139
Effect of the super-flux cellulose triacetate dialyser membrane on the removal of non-protein-bound and protein-bound uraemic solutes.	2007 Jul	17468506
Effects of uremic serum and uremic toxins on hepatic uptake of digoxin.	2008 Oct	18708994
Recent progress in the analysis of uremic toxins by mass spectrometry.	2009 Sep 1	19083276
Proximal tubule cell hypothesis for cardiorenal syndrome in diabetes.	2010 Dec 9	21197105
Inhibitory effects of uraemic toxins 3-indoxyl sulfate and p-cresol on losartan metabolism in vitro.	2010 Jan	20723009

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:35:27 GMT 2023` Edited by `admin` on `Sat Dec 16 11:35:27 GMT 2023`
Record UNII	JTU41879GF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-(2-CARBOXYETHYL)-4-METHYL-5-PROPYLFURAN-3-CARBOXYLICACID

Systematic Name

English

CMPF

Common Name

English

3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC

Systematic Name

English

PROPYLUROFURANIC ACID

Common Name

English

2-FURANPROPIONIC ACID, 3-CARBOXY-4-METHYL-5-PROPYL-

Systematic Name

English

Code System Code Type Description

CAS

86879-39-2