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Details

Stereochemistry ACHIRAL
Molecular Formula C17H18F2N2
Molecular Weight 288.335
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1-(Bis(4-fluorophenyl)methyl)piperazine

SMILES

FC1=CC=C(C=C1)C(N2CCNCC2)C3=CC=C(F)C=C3

InChI

InChIKey=TTXIFFYPVGWLSE-UHFFFAOYSA-N
InChI=1S/C17H18F2N2/c18-15-5-1-13(2-6-15)17(21-11-9-20-10-12-21)14-3-7-16(19)8-4-14/h1-8,17,20H,9-12H2

HIDE SMILES / InChI

Molecular Formula C17H18F2N2
Molecular Weight 288.335
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
{[1-(Arylmethyl)piperidin-4-yl]oxy}-(trifluoromethyl)-pyridines: ketanserin analogues with insect growth regulating activity.
2008-09
Synthesis and in vitro antimicrobial studies of medicinally important novel N-alkyl and N-sulfonyl derivatives of 1-[bis(4-fluorophenyl)-methyl]piperazine.
2006-10-01
Synthesis and efficacy of 1-[bis(4-fluorophenyl)-methyl]piperazine derivatives for acetylcholinesterase inhibition, as a stimulant of central cholinergic neurotransmission in Alzheimer's disease.
2006-08-01
Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8.
2005-02-01
Patents
Substance Class Chemical
Created
by admin
on Tue Apr 01 17:48:28 GMT 2025
Edited
by admin
on Tue Apr 01 17:48:28 GMT 2025
Record UNII
JT57UD83SY
Record Status Validated (UNII)
Record Version
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Name Type Language
FLUNARIZINE DIHYDROCHLORIDE IMPURITY A [EP IMPURITY]
Preferred Name English
1-(Bis(4-fluorophenyl)methyl)piperazine
Systematic Name English
Piperazine, 1-[bis(4-fluorophenyl)methyl]-
Systematic Name English
Code System Code Type Description
ECHA (EC/EINECS)
248-476-0
Created by admin on Tue Apr 01 17:48:28 GMT 2025 , Edited by admin on Tue Apr 01 17:48:28 GMT 2025
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FDA UNII
JT57UD83SY
Created by admin on Tue Apr 01 17:48:28 GMT 2025 , Edited by admin on Tue Apr 01 17:48:28 GMT 2025
PRIMARY
PUBCHEM
152932
Created by admin on Tue Apr 01 17:48:28 GMT 2025 , Edited by admin on Tue Apr 01 17:48:28 GMT 2025
PRIMARY
EPA CompTox
DTXSID8057699
Created by admin on Tue Apr 01 17:48:28 GMT 2025 , Edited by admin on Tue Apr 01 17:48:28 GMT 2025
PRIMARY
CAS
27469-60-9
Created by admin on Tue Apr 01 17:48:28 GMT 2025 , Edited by admin on Tue Apr 01 17:48:28 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> IMPURITY