1-(Bis(4-fluorophenyl)methyl)piperazine

FC1=CC=C(C=C1)C(N2CCNCC2)C3=CC=C(F)C=C3

InChIKey=TTXIFFYPVGWLSE-UHFFFAOYSA-N

InChI=1S/C17H18F2N2/c18-15-5-1-13(2-6-15)17(21-11-9-20-10-12-21)14-3-7-16(19)8-4-14/h1-8,17,20H,9-12H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8.	2005 Feb 1	15664838
Synthesis and efficacy of 1-[bis(4-fluorophenyl)-methyl]piperazine derivatives for acetylcholinesterase inhibition, as a stimulant of central cholinergic neurotransmission in Alzheimer's disease.	2006 Aug 1	16735118
Synthesis and in vitro antimicrobial studies of medicinally important novel N-alkyl and N-sulfonyl derivatives of 1-[bis(4-fluorophenyl)-methyl]piperazine.	2006 Oct 1	16784863
{[1-(Arylmethyl)piperidin-4-yl]oxy}-(trifluoromethyl)-pyridines: ketanserin analogues with insect growth regulating activity.	2008 Sep	18816514

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 12:01:50 GMT 2023` Edited by `admin` on `Sat Dec 16 12:01:50 GMT 2023`
Record UNII	JT57UD83SY
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

1-(Bis(4-fluorophenyl)methyl)piperazine

Systematic Name

English

FLUNARIZINE DIHYDROCHLORIDE IMPURITY A [EP IMPURITY]

Common Name

English

Piperazine, 1-[bis(4-fluorophenyl)methyl]-

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

248-476-0