U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Wed Apr 02 19:25:49 GMT 2025
Edited
by admin
on Wed Apr 02 19:25:49 GMT 2025
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Retroviridae
Organism Genus Lentivirus
Organism Species human immunodeficiency virus 1
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name SIN/LV/MAGE-A4 c1032 TCR/CD8?
Part whole
Record UNII
JT3Q2MC2MT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Uzatresgene autoleucel vector encoding MAGE-A4 specific T cell receptor (TCR) plus CD8 alpha co-receptor
Preferred Name English
Code System Code Type Description
FDA UNII
JT3Q2MC2MT
Created by admin on Wed Apr 02 19:25:49 GMT 2025 , Edited by admin on Wed Apr 02 19:25:49 GMT 2025
PRIMARY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR Uzatresgene autoleucel transgene insert encoding MAGE-A4 specific T cell receptor (TCR) plus CD8 alpha co-receptor 3AL52683ZL