Famtozinameran

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 19:27:17 UTC 2023` Edited by `admin` on `Sat Dec 16 19:27:17 UTC 2023`
Nucleic Acid Type	mRNA VACCINE
Nucleic Acid Subtype	TRANSGENE
Sequence Origin	VIRAL
Sequence Type	COMPLETE
Record UNII	JSV288Q5CV
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Famtozinameran

Official Name

English

RNA (recombinant 5′-[1,2-[(3′-O-methyl)m7G-(5′→5′)-ppp-Am]]-capped all uridine→N1-methylpseudouridine-substituted severe acute respiratory syndrome coronavirus 2 spike glycoprotein secretory signal peptide plus codon-optimized pre-fusion spik

Common Name

English

BNT162b2 Omicron (BA.4/BA.5) mRNA

Common Name

English

BNT162b2 Omicron (BA.4/BA.5)

Code

English

famtozinameran [INN]

Common Name

English

Code System Code Type Description

SMS_ID

300000046473

Created by admin on Sat Dec 16 19:27:18 UTC 2023 , Edited by admin on Sat Dec 16 19:27:18 UTC 2023

PRIMARY

NCI_THESAURUS

C190751

Created by admin on Sat Dec 16 19:27:18 UTC 2023 , Edited by admin on Sat Dec 16 19:27:18 UTC 2023

PRIMARY

INN

12809

Created by admin on Sat Dec 16 19:27:18 UTC 2023 , Edited by admin on Sat Dec 16 19:27:18 UTC 2023

PRIMARY

DAILYMED

JSV288Q5CV

Created by admin on Sat Dec 16 19:27:18 UTC 2023 , Edited by admin on Sat Dec 16 19:27:18 UTC 2023

PRIMARY

FDA UNII

JSV288Q5CV

Created by admin on Sat Dec 16 19:27:18 UTC 2023 , Edited by admin on Sat Dec 16 19:27:18 UTC 2023

PRIMARY

Sugar	Site Range	Site Count
D-Ribose (RNA)	1_1-1_4268	4268 / 4268

Linkage	Site Range	Site Count
Phosphate	1_2-1_4268	4267 / 4267

Related Record Type Details


					HXN9XQ9CL3

BNT162b2 Omicron (BA.4/BA.5) unprocessed expressed protein

EXPRESSED PROTEIN->VECTOR

Amount:


					B6L4N5Z4GH

SARS-COV2

TARGET ORGANISM->VACCINE ANTIGEN

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOSIDE_SUBSTITUTION			U		N1-METHYLPSEUDOURIDINE	09RAD4M6WF
NUCLEOTIDE SUBSTITUTION	[1_1]	5'-TERMINUS		Amount:	m2-7,3’-OGppp(m1-2’-O)Ap mRNA CAP	VNP8CZY34V