Details
Stereochemistry | ACHIRAL |
Molecular Formula | 2Br.2Hg |
Molecular Weight | 560.99 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Br-].[Br-].[Hg+].[Hg+]
InChI
InChIKey=RVARJMCTILSHND-UHFFFAOYSA-L
InChI=1S/2BrH.2Hg/h2*1H;;/q;;2*+1/p-2
Molecular Formula | Hg |
Molecular Weight | 200.59 |
Charge | 1 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | BrH |
Molecular Weight | 80.912 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Mercury(I) iodide is a chemical compound that has been used as a drug in the 19th century, sometimes under the contemporary name of 'protiodide of mercury'. Mercury(I) iodide was used to treat a wide range of conditions; everything from acne to kidney disease and in particular was the treatment of choice for syphilis. It was available over the counter at any drugstore in the world, the most common form being a concoction of protiodide, licorice, glycerin, and marshmallow. Taken orally, and in low doses, protiodide causes excessive salivation, fetid breath, spongy and bleeding gums, and sore teeth. Excessive use or an overdose causes physical weakness, loss of teeth, hemolysing (destruction of the red blood cells) of the blood and necrosis of the bones and tissues of the body. Early signs of an overdose or excessive use are muscular tremors, chorea, and locomotor ataxia. Violent bloody vomiting and voiding also occur.
Approval Year
PubMed
Title | Date | PubMed |
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NEPHROTIC SYNDROME CAUSED BY PROTIODIDE OF MERCURY. | 1965 Mar |
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Investigations into black extrinsic tooth stain. | 1977 Aug |
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Convulsions following application of gamma benzene hexachloride. | 1981 Jul |
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Clinical comparison of two radiocolloids for internal mammary lymphoscintigraphy. | 1985 Dec |
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Widespread occurrence of bacterial thiol methyltransferases and the biogenic emission of methylated sulfur gases. | 1987 Jul |
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Activity of polymorphonuclear leukocytes in the presence of sulfide. | 1989 Sep |
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Lung dysfunction in animal confinement workers--chairman's report to the Scientific Committee of the Third International Symposium: issues in health, safety and agriculture, held in Saskatoon, Saskatchewan, Canada, May 10-15, 1992. | 1992 |
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Chemosensory event-related potentials in the investigation of interactions between the olfactory and the somatosensory (trigeminal) systems. | 1992 Sep |
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The usefulness of thiosulfate as an indicator of hydrogen sulfide poisoning: three cases. | 1997 |
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A fatal case of hydrogen sulfide poisoning in a geothermal power plant. | 1998 Jul |
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Hydrogen sulfide and colonic epithelial metabolism: implications for ulcerative colitis. | 2001 Aug |
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Gas production by feces of infants. | 2001 May |
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HG/LT-GC/ICP-MS coupling for identification of metal(loid) species in human urine after fish consumption. | 2001 Nov |
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Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE. | 2002 |
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Fatal and nonfatal poisoning by hydrogen sulfide at an industrial waste site. | 2002 May |
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Novel neural modulators. | 2003 |
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A salivary incubation test for evaluation of oral malodor: a pilot study. | 2003 Jul |
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Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine. | 2004 Dec 10 |
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Major and trace elements in whole blood of phlebotomized patients with porphyria cutanea tarda. | 2005 |
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The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis. | 2005 Sep |
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Emergency room visits for respiratory conditions in children increased after Guagua Pichincha volcanic eruptions in April 2000 in Quito, Ecuador observational study: time series analysis. | 2007 Jul 24 |
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Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder. | 2008 Feb |
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Contractile and vasorelaxant effects of hydrogen sulfide and its biosynthesis in the human internal mammary artery. | 2008 Feb |
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Disulfides as cyanide antidotes: evidence for a new in vivo oxidative pathway for cyanide detoxification. | 2009 Dec |
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Multiple protective activities of neuroglobin in cultured neuronal cells exposed to hypoxia re-oxygenation injury. | 2009 Mar |
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HIF-1 and SKN-1 coordinate the transcriptional response to hydrogen sulfide in Caenorhabditis elegans. | 2011 |
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Time-series analysis of mortality effects of fine particulate matter components in Detroit and Seattle. | 2011 Apr |
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S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism. | 2011 Jun |
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Detoxification of methylmercury by hydrogen sulfide-producing enzyme in Mammalian cells. | 2011 Oct 17 |
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Indoor air pollutants and health in the United Arab Emirates. | 2012 May |
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A novel mechanism of formaldehyde neurotoxicity: inhibition of hydrogen sulfide generation by promoting overproduction of nitric oxide. | 2013 |
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Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells. | 2013 Jul |
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Dexamethasone ameliorates H₂S-induced acute lung injury by alleviating matrix metalloproteinase-2 and -9 expression. | 2014 |
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Downregulation of cystathionine β-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type. | 2014 Aug 22 |
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H2S inhibition of chemical hypoxia-induced proliferation of HPASMCs is mediated by the upregulation of COX-2/PGI2. | 2014 Feb |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 17:12:02 UTC 2023
by
admin
on
Fri Dec 15 17:12:02 UTC 2023
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Record UNII |
JSJ4936A2S
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Record Status |
Validated (UNII)
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Record Version |
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-
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24829
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JSJ4936A2S
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JSJ4936A2S
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m7231
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10031-18-2
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Mercurous bromide
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DTXSID901336726
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1221
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