COENZYME Q1

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H18O4
Molecular Weight	250.2903
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O

InChI

InChIKey=SOECUQMRSRVZQQ-UHFFFAOYSA-N

InChI=1S/C14H18O4/c1-8(2)6-7-10-9(3)11(15)13(17-4)14(18-5)12(10)16/h6H,7H2,1-5H3

HIDE SMILES / InChI

Molecular Formula	C14H18O4
Molecular Weight	250.2903
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Discharge of newly-synthesized dolichol and ubiquinone with lipoproteins to rat liver perfusate and to the bile.	1989 Nov	2615561
Ubiquinone, dolichol, and cholesterol metabolism in aging and Alzheimer's disease.	1992 Jun	1449707
Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-term simvastatin treatment in humans.	1995 Jan	7828383
Muscle ubiquinone in male effort angina patients.	1996 Mar 23	9095475
Muscle ubiquinone in healthy physically active males.	1996 Mar 23	9095474
Simultaneous detection of ubiquinol and ubiquinone in human plasma as a marker of oxidative stress.	1997 Jul 15	9234900
Analysis of ubiquinone and tocopherol levels in normal and hyperlipidemic human plasma.	1998 Aug	9727612
Relationship between sperm cell ubiquinone and seminal parameters in subjects with and without varicocele.	1998 Feb-Mar	9567163
Retention of heme in axial ligand mutants of succinate-ubiquinone xxidoreductase (complex II) from Escherichia coli.	2001 Jun 1	11259408
Interaction of purified NDH-1 from Escherichia coli with ubiquinone analogues.	2002 Feb 15	11997136
Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA.	2003	14695926
NADH-Ubiquinone oxidoreductase: substrate-dependent oxygen turnover to superoxide anion as a function of flavin mononucleotide.	2003 Oct	16120348
Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I.	2004 Dec 2	15577909
Simultaneous determination of ubiquinol and ubiquinone in skeletal muscle of pediatric patients.	2005 Jul 15	15989930
Theoretical study of the energetics of the reactions of triplet dioxygen with hydroquinone, semiquinone, and their protonated forms: relation to the mechanism of superoxide generation in the respiratory chain.	2007 Apr 5	17388501
HQNO-sensitive NADH:quinone oxidoreductase of Bacillus cereus KCTC 3674.	2007 Jan 31	17244482
Oxidant-induced formation of a neutral flavosemiquinone in the Na+-translocating NADH:Quinone oxidoreductase (Na+-NQR) from Vibrio cholerae.	2008 Jul-Aug	18454933
Activity of 1,4-benzoquinones against formosan subterranean termites (Coptotermes formosanus).	2008 Jun 11	18461966
Platinum nanoparticles have an activity similar to mitochondrial NADH:ubiquinone oxidoreductase.	2008 Oct 15	18653320
Properties of the thioredoxin fold superfamily are modulated by a single amino acid residue.	2009 Apr 10	19181668
Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species.	2009 Mar 10	19220002
PGC-1-related coactivator modulates mitochondrial-nuclear crosstalk through endogenous nitric oxide in a cellular model of oncocytic thyroid tumours.	2009 Nov 23	19956726
Polymyxin B identified as an inhibitor of alternative NADH dehydrogenase and malate: quinone oxidoreductase from the Gram-positive bacterium Mycobacterium smegmatis.	2009 Oct	19564154
Old and new inhibitors of quinone reductase 2.	2010 Jul 30	20399199
Purification and characterization of Put1p from Saccharomyces cerevisiae.	2010 Jun 15	20450881
Loss of estrogen receptor beta decreases mitochondrial energetic potential and increases thrombogenicity of platelets in aged female mice.	2010 Mar	19908165
Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice.	2010 Sep 13	20856881

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:45:13 GMT 2023` Edited by `admin` on `Sat Dec 16 08:45:13 GMT 2023`
Record UNII	JR17826E4G
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

COENZYME Q1

Common Name

English

2,3-DIMETHOXY-5-METHYL-6-(3-METHYLBUT-2-EN-1-YL)CYCLOHEXA-2,5-DIENE-1,4-DIONE

Systematic Name

English

CO-Q1

Common Name

English

2,5-CYCLOHEXADIENE-1,4-DIONE, 2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTEN-1-YL)-

Systematic Name

English

COQ1

Common Name

English

UBIQUINONE Q5

Common Name

English

2-ISOPENTENYL-5,6-DIMETHOXY-3-METHYL-P-BENZOQUINONE

Common Name

English

2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTENYL)-1,4-BENZOQUINONE

Systematic Name

English

UBIQUINONE Q1

Common Name

English

UBIQUINONE 5

Common Name

English

J93.220E

Code

English

P-BENZOQUINONE, 2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTENYL)-

Common Name

English

UQ1

Common Name

English

NSC-268269

Code

English

UBIQUIONONE 1

Common Name

English

2,5-CYCLOHEXADIENE-1,4-DIONE, 2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTENYL)-

Systematic Name

English

KOENZYM Q

Common Name

English

UBIQUINONE-Q1

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID10223001