COENZYME Q1

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H18O4
Molecular Weight	250.2903
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O

InChI

InChIKey=SOECUQMRSRVZQQ-UHFFFAOYSA-N

InChI=1S/C14H18O4/c1-8(2)6-7-10-9(3)11(15)13(17-4)14(18-5)12(10)16/h6H,7H2,1-5H3

HIDE SMILES / InChI

Molecular Formula	C14H18O4
Molecular Weight	250.2903
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice.	2010-09-13	20856881
Old and new inhibitors of quinone reductase 2.	2010-07-30	20399199
Purification and characterization of Put1p from Saccharomyces cerevisiae.	2010-06-15	20450881
Loss of estrogen receptor beta decreases mitochondrial energetic potential and increases thrombogenicity of platelets in aged female mice.	2010-03	19908165
PGC-1-related coactivator modulates mitochondrial-nuclear crosstalk through endogenous nitric oxide in a cellular model of oncocytic thyroid tumours.	2009-11-23	19956726
Polymyxin B identified as an inhibitor of alternative NADH dehydrogenase and malate: quinone oxidoreductase from the Gram-positive bacterium Mycobacterium smegmatis.	2009-10	19564154
Properties of the thioredoxin fold superfamily are modulated by a single amino acid residue.	2009-04-10	19181668
Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species.	2009-03-10	19220002
Platinum nanoparticles have an activity similar to mitochondrial NADH:ubiquinone oxidoreductase.	2008-10-15	18653320
Activity of 1,4-benzoquinones against formosan subterranean termites (Coptotermes formosanus).	2008-06-11	18461966
Oxidant-induced formation of a neutral flavosemiquinone in the Na+-translocating NADH:Quinone oxidoreductase (Na+-NQR) from Vibrio cholerae.	2008-01-30	18454933
Theoretical study of the energetics of the reactions of triplet dioxygen with hydroquinone, semiquinone, and their protonated forms: relation to the mechanism of superoxide generation in the respiratory chain.	2007-04-05	17388501
HQNO-sensitive NADH:quinone oxidoreductase of Bacillus cereus KCTC 3674.	2007-01-31	17244482
Simultaneous determination of ubiquinol and ubiquinone in skeletal muscle of pediatric patients.	2005-07-15	15989930
Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I.	2004-12-02	15577909
NADH-Ubiquinone oxidoreductase: substrate-dependent oxygen turnover to superoxide anion as a function of flavin mononucleotide.	2003-10	16120348
Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA.	2003	14695926
Interaction of purified NDH-1 from Escherichia coli with ubiquinone analogues.	2002-02-15	11997136
Retention of heme in axial ligand mutants of succinate-ubiquinone xxidoreductase (complex II) from Escherichia coli.	2001-06-01	11259408
Analysis of ubiquinone and tocopherol levels in normal and hyperlipidemic human plasma.	1998-08	9727612
Relationship between sperm cell ubiquinone and seminal parameters in subjects with and without varicocele.	1998-05-06	9567163
Simultaneous detection of ubiquinol and ubiquinone in human plasma as a marker of oxidative stress.	1997-07-15	9234900
Muscle ubiquinone in male effort angina patients.	1996-03-23	9095475
Muscle ubiquinone in healthy physically active males.	1996-03-23	9095474
Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-term simvastatin treatment in humans.	1995-01	7828383
Ubiquinone, dolichol, and cholesterol metabolism in aging and Alzheimer's disease.	1992-06	1449707
Discharge of newly-synthesized dolichol and ubiquinone with lipoproteins to rat liver perfusate and to the bile.	1989-11	2615561

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:17:29 GMT 2025` Edited by `admin` on `Mon Mar 31 22:17:29 GMT 2025`
Record UNII	JR17826E4G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

J93.220E

Preferred Name

English

COENZYME Q1

Common Name

English

2,3-DIMETHOXY-5-METHYL-6-(3-METHYLBUT-2-EN-1-YL)CYCLOHEXA-2,5-DIENE-1,4-DIONE

Systematic Name

English

CO-Q1

Common Name

English

2,5-CYCLOHEXADIENE-1,4-DIONE, 2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTEN-1-YL)-

Systematic Name

English

COQ1

Common Name

English

UBIQUINONE Q5

Common Name

English

2-ISOPENTENYL-5,6-DIMETHOXY-3-METHYL-P-BENZOQUINONE

Common Name

English

2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTENYL)-1,4-BENZOQUINONE

Systematic Name

English

UBIQUINONE Q1

Common Name

English

UBIQUINONE 5

Common Name

English

P-BENZOQUINONE, 2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTENYL)-

Common Name

English

UQ1

Common Name

English

NSC-268269

Code

English

UBIQUIONONE 1

Common Name

English

2,5-CYCLOHEXADIENE-1,4-DIONE, 2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTENYL)-

Systematic Name

English

KOENZYM Q

Common Name

English

UBIQUINONE-Q1

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID10223001