Lancastotug

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 20:11:09 GMT 2023` Edited by `admin` on `Sat Dec 16 20:11:09 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	JP3KZB9R7C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Lancastotug

Official Name

English

AK127

Code

English

Gamma1 heavy chain humanized (1-451) [VH (Homo sapiens IGHV4-30-4*01 (90.8%) -(IGHD) -IGHJ4*01 (92.3%) L123>S (116), CDR-IMGT [9.7.14] (26-34.52-58.97-110)) (1-121) -Homo sapiens IGHG1*03v,G1m3>G1m17, nG1m1, CH1 K120, CH3 E12, M14 (CH1R120>K (218) (122-2

Common Name

English

mmunoglobulin G1-kappa, anti-[Homo sapiens TIGIT (T cell immunoreceptor with Ig domain and ITIM, V-set Ig member 9, VSIG9, V-set and transmembrane member 3, VSTM3)], humanized monoclonal antibody

Common Name

English

Immunoglobulin G1, anti-(human receptor TIGIT) (human-Mus musculus monoclonal AK127 γ1-chain), disulfide with human-Mus musculus monoclonal AK127 κ-chain, dimer

Common Name

English

lancastotug [INN]

Common Name

English

AK-127

Code

English

Code System Code Type Description

INN

12727

Created by admin on Sat Dec 16 20:11:10 GMT 2023 , Edited by admin on Sat Dec 16 20:11:10 GMT 2023

PRIMARY

FDA UNII

JP3KZB9R7C

Created by admin on Sat Dec 16 20:11:10 GMT 2023 , Edited by admin on Sat Dec 16 20:11:10 GMT 2023

PRIMARY

CAS

2768355-20-8

Created by admin on Sat Dec 16 20:11:10 GMT 2023 , Edited by admin on Sat Dec 16 20:11:10 GMT 2023

PRIMARY

Related Record Type Details


					3GY58DVB2F

T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS

TARGET->LIGAND

Amount:

Related Record Type Details


					JP3KZB9R7C

Lancastotug

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL