VOFATAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:09:28 UTC 2023` Edited by `admin` on `Sat Dec 16 14:09:28 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	JMH6YR91PG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VOFATAMAB

Official Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS FGFR3 (FIBROBLAST GROWTH FACTOR RECEPTOR 3, CD333)), MONOCLONAL ANTIBODYGAMMA1 HEAVY CHAIN (1-457) (VH (HOMO SAPIENS IGHV3-66*01 (85.7%)-(IGHD)-IGHJ4*01 (100%)) (8.8.20) (1-127)-HOMO SAPIENS IGHG1*03V, G1M3>G1M

Systematic Name

English

B-701

Code

English

MFGR1877A

Code

English

ANTI-FGR3

Code

English

VOFATAMAB [USAN]

Common Name

English

MFGR-1877S

Code

English

B701

Code

English

vofatamab [INN]

Common Name

English

ANTI-FGFR3 MONOCLONAL ANTIBODY MFGR1877S

Common Name

English

MFGR1877S

Code

English

Vofatamab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN FIBROBLAST GROWTH FACTOR RECEPTOR TYPE 3) (HUMAN MONOCLONAL MFGR1877S HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MFGR1877S .KAPPA.-CHAIN, DIMER

Systematic Name

English

MFGR 1877S [WHO-DD]

Common Name

English

RG-7444

Code

English

RG7444

Code

English

MFGR-1877A

Code

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR-3, ANTIGEN CD333))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-457) (HOMO SAPIENS VH (IGHV3-66*01 (86%) (IGHD)-IGHJ4*01) (8.8.20) (1-127)-HOMO SAPIENS IGHG1*03

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129822

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

NCI_THESAURUS

C133879

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

NCI_THESAURUS

C20401

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

Code System Code Type Description

CAS

1639359-81-1

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

ALTERNATIVE

DRUG BANK

DB14781

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

PRIMARY

USAN

EF-149

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

PRIMARY

NCI_THESAURUS

C116863

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

PRIMARY

INN

10919

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

PRIMARY

FDA UNII

JMH6YR91PG

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

PRIMARY

CAS

1312305-12-6

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

PRIMARY

NCI_THESAURUS

C103859

Created by admin on Sat Dec 16 14:09:28 UTC 2023 , Edited by admin on Sat Dec 16 14:09:28 UTC 2023

NO STRUCTURE GIVEN

From	To
1_22	1_96
2_22	2_96
2_154	2_210
2_230	4_214
2_271	2_331
1_154	1_210
2_377	2_435
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_230	3_214
1_236	2_236
1_239	2_239
1_271	1_331
1_377	1_435

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_307
N	2_307

Related Record Type Details


					L01TYM08QX

FIBROBLAST GROWTH FACTOR RECEPTOR 3

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					JMH6YR91PG

VOFATAMAB

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL