U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Mon Oct 21 20:15:58 UTC 2019
Edited
by admin
on Mon Oct 21 20:15:58 UTC 2019
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
JMH6YR91PG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VOFATAMAB
USAN  
Official Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS FGFR3 (FIBROBLAST GROWTH FACTOR RECEPTOR 3, CD333)), MONOCLONAL ANTIBODYGAMMA1 HEAVY CHAIN (1-457) (VH (HOMO SAPIENS IGHV3-66*01 (85.7%)-(IGHD)-IGHJ4*01 (100%)) (8.8.20) (1-127)-HOMO SAPIENS IGHG1*03V, G1M3>G1M
Systematic Name English
B-701
Code English
MFGR1877A
Code English
ANTI-FGR3
Code English
VOFATAMAB [USAN]
Common Name English
MFGR-1877S
Code English
VOFATAMAB [INN]
Common Name English
ANTI-FGFR3 MONOCLONAL ANTIBODY MFGR1877S
Common Name English
MFGR1877S
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN FIBROBLAST GROWTH FACTOR RECEPTOR TYPE 3) (HUMAN MONOCLONAL MFGR1877S HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MFGR1877S .KAPPA.-CHAIN, DIMER
Systematic Name English
RG-7444
Code English
B-701 [WHO-DD]
Common Name English
MFGR-1877A
Code English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR-3, ANTIGEN CD333))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-457) (HOMO SAPIENS VH (IGHV3-66*01 (86%) (IGHD)-IGHJ4*01) (8.8.20) (1-127)-HOMO SAPIENS IGHG1*03
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C129822
Created by admin on Mon Oct 21 20:15:58 UTC 2019 , Edited by admin on Mon Oct 21 20:15:58 UTC 2019
NCI_THESAURUS C133879
Created by admin on Mon Oct 21 20:15:58 UTC 2019 , Edited by admin on Mon Oct 21 20:15:58 UTC 2019
NCI_THESAURUS C20401
Created by admin on Mon Oct 21 20:15:58 UTC 2019 , Edited by admin on Mon Oct 21 20:15:58 UTC 2019
Code System Code Type Description
CAS
1639359-81-1
Created by admin on Mon Oct 21 20:15:58 UTC 2019 , Edited by admin on Mon Oct 21 20:15:58 UTC 2019
ALTERNATIVE
INN
10919
Created by admin on Mon Oct 21 20:15:58 UTC 2019 , Edited by admin on Mon Oct 21 20:15:58 UTC 2019
PRIMARY
NCI_THESAURUS
C103859
Created by admin on Mon Oct 21 20:15:58 UTC 2019 , Edited by admin on Mon Oct 21 20:15:58 UTC 2019
PRIMARY
CAS
1312305-12-6
Created by admin on Mon Oct 21 20:15:58 UTC 2019 , Edited by admin on Mon Oct 21 20:15:58 UTC 2019
PRIMARY
From To
1_22 1_96
2_22 2_96
2_154 2_210
2_230 4_214
2_271 2_331
1_154 1_210
2_377 2_435
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_230 3_214
1_236 2_236
1_239 2_239
1_271 1_331
1_377 1_435
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_307
N 2_307
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL