Oturkibart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 19:11:23 GMT 2025` Edited by `admin` on `Wed Apr 02 19:11:23 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED RABBIT
Sequence Type	COMPLETE
Record UNII	JL575J4HUJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

QX-005N

Preferred Name

English

Oturkibart

Official Name

English

Immunoglobulin G4 [225-proline], anti-(human interleukin 4 receptor ?) (human-Oryctolagus cuniculus monoclonal QX005N ?4-chain), disulfide with human-Oryctolagus cuniculus monoclonal QX005N ?-chain, dimer

Common Name

English

immunoglobulin G4-kappa, anti-[Homo sapiens IL4R (interleukin 4 receptor, IL4RA, IL-4RA, interleukin 13 receptor, CD124)], humanized monoclonal antibody (oturkibart)

Common Name

English

H-gamma4 heavy chain humanized (1-444) [VH (Homo sapiens IGHV3-66*01 (83.5%) -(IGHD) -IGHJ2*01 (85.7%) R120>Q (109), CDR-IMGT [8.7.11] (26-33.51-57.96-106)) (1-117) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10 (CH1 (118-215), hinge 1-12 S10>P (

Common Name

English

oturkibart [INN]

Common Name

English

QX005N

Code

English

Code System Code Type Description

INN

13526

Created by admin on Wed Apr 02 19:11:23 GMT 2025 , Edited by admin on Wed Apr 02 19:11:23 GMT 2025

PRIMARY

CAS

2956767-43-2

Created by admin on Wed Apr 02 19:11:23 GMT 2025 , Edited by admin on Wed Apr 02 19:11:23 GMT 2025

PRIMARY

FDA UNII

JL575J4HUJ

Created by admin on Wed Apr 02 19:11:23 GMT 2025 , Edited by admin on Wed Apr 02 19:11:23 GMT 2025

PRIMARY

From	To
1_22	1_95
2_22	2_95
2_131	4_217
2_144	2_200
2_258	2_318
1_131	3_217
2_364	2_422
3_23	3_90
3_137	3_197
4_23	4_90
4_137	4_197
1_144	1_200
1_223	2_223
1_226	2_226
1_258	1_318
1_364	1_422