U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Mixture
Created
by admin
on Sat Dec 16 11:35:32 GMT 2023
Edited
by admin
on Sat Dec 16 11:35:32 GMT 2023
Record UNII
JIY1ILR284
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HUMAN BILE ACIDS
Common Name English
Code System Code Type Description
FDA UNII
JIY1ILR284
Created by admin on Sat Dec 16 11:35:32 GMT 2023 , Edited by admin on Sat Dec 16 11:35:32 GMT 2023
PRIMARY
WIKIPEDIA
Bile acid
Created by admin on Sat Dec 16 11:35:32 GMT 2023 , Edited by admin on Sat Dec 16 11:35:32 GMT 2023
PRIMARY Bile acids are steroid acids found predominantly in the bile of mammals and other vertebrates. Different molecular forms of bile acids can be synthesized in the liver by different species. Bile acids are conjugated with taurine or glycine in the liver, forming bile salts.Primary bile acids are those synthesized by the liver. Secondary bile acids result from bacterial actions in the colon. In humans, taurocholic acid and glycocholic acid (derivatives of cholic acid) and taurochenodeoxycholic acid and glycochenodeoxycholic acid (derivatives of chenodeoxycholic acid) are the major bile salts in bile and are roughly equal in concentration. The conjugated salts of their 7-alpha-dehydroxylated derivatives, deoxycholic acid and lithocholic acid, are also found, with derivatives of cholic, chenodeoxycholic and deoxycholic acids accounting for over 90% of human biliary bile acids.
Related Record Type Details
TRANSPORTER -> SUBSTRATE
TRANSPORTER -> SUBSTRATE
TRANSPORTER -> SUBSTRATE
Definition References