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Approval Year

Substance Class Mixture
Created
by admin
on Sat Jun 26 23:25:33 UTC 2021
Edited
by admin
on Sat Jun 26 23:25:33 UTC 2021
Record UNII
JIY1ILR284
Record Status Validated (UNII)
Record Version
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Name Type Language
HUMAN BILE ACIDS
Common Name English
Code System Code Type Description
WIKIPEDIA
Bile acid
Created by admin on Sat Jun 26 23:25:33 UTC 2021 , Edited by admin on Sat Jun 26 23:25:33 UTC 2021
PRIMARY Bile acids are steroid acids found predominantly in the bile of mammals and other vertebrates. Different molecular forms of bile acids can be synthesized in the liver by different species. Bile acids are conjugated with taurine or glycine in the liver, forming bile salts.Primary bile acids are those synthesized by the liver. Secondary bile acids result from bacterial actions in the colon. In humans, taurocholic acid and glycocholic acid (derivatives of cholic acid) and taurochenodeoxycholic acid and glycochenodeoxycholic acid (derivatives of chenodeoxycholic acid) are the major bile salts in bile and are roughly equal in concentration. The conjugated salts of their 7-alpha-dehydroxylated derivatives, deoxycholic acid and lithocholic acid, are also found, with derivatives of cholic, chenodeoxycholic and deoxycholic acids accounting for over 90% of human biliary bile acids.
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Definition References