TECHNETIUM TC-99M CYCLOBUTYL PROPYLENE AMINE OXIME

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C14H25N4O2.OTc
Molecular Weight	396.2796
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	2
Charge	0
Stereo Comments	Assumed (R,R)-(E,E) isomer as in HM-PAO

SHOW SMILES / InChI

Structure of TECHNETIUM TC-99M CYCLOBUTYL PROPYLENE AMINE OXIME

Structure Search

SMILES

O=[99Tc+3].C[C@@H]([N-]CC1(C[N-][C@H](C)C(\C)=N\[O-])CCC1)C(\C)=N\O

InChI

InChIKey=SYRDLYTYTQOQFZ-NQPMITLXSA-M

InChI=1S/C14H26N4O2.O.Tc/c1-10(12(3)17-19)15-8-14(6-5-7-14)9-16-11(2)13(4)18-20;;/h10-11,19-20H,5-9H2,1-4H3;;/q-2;;+3/p-1/b17-12+,18-13+;;/t10-,11-;;/m1../s1/i;;1+1

HIDE SMILES / InChI

Molecular Formula	OTc
Molecular Weight	114.9057
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C14H26N4O2
Molecular Weight	282.3818
Charge	-2
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	2
Optical Activity	UNSPECIFIED

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2596
bone problems 40 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8583	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 40 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8583	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012 Oct	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:03:16 GMT 2025` Edited by `admin` on `Mon Mar 31 18:03:16 GMT 2025`
Record UNII	JH18E0A8W1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TC-99M CB-PAO

Preferred Name

English

TECHNETIUM TC-99M CYCLOBUTYL PROPYLENE AMINE OXIME

Common Name

English

2-BUTANONE, 3,3'-(CYCLOBUTYLIDENEBIS(METHYLENEIMINO))BIS-, DIOXIME, TECHNETIUM-99 COMPLEX

Systematic Name

English

TECHNETIUM-99TC, ((3,3'-(CYCLOBUTYLIDENEBIS(METHYLENEIMINO-.KAPPA.N))BIS(2-BUTANONE) DI(OXIMATO-.KAPPA.N))(3-))OXO-, (SP-5-15-(R*,R*))-

Systematic Name

English

Code System Code Type Description

FDA UNII

JH18E0A8W1

Created by admin on Mon Mar 31 18:03:16 GMT 2025 , Edited by admin on Mon Mar 31 18:03:16 GMT 2025

PRIMARY

PUBCHEM

134160132

Created by admin on Mon Mar 31 18:03:16 GMT 2025 , Edited by admin on Mon Mar 31 18:03:16 GMT 2025

PRIMARY

CAS

131315-61-2

Created by admin on Mon Mar 31 18:03:16 GMT 2025 , Edited by admin on Mon Mar 31 18:03:16 GMT 2025

PRIMARY

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TECHNETIUM TC-99M

ACTIVE MOIETY

Details

SMILES

InChI

Approval Year

Conditions

Approved Use

Launch Date

Approved Use

Launch Date

PubMed

Patents

Sample Use Guides