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Details

Stereochemistry ABSOLUTE
Molecular Formula C14H25N4O2.OTc
Molecular Weight 396.2796
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 2
Charge 0
Stereo Comments Assumed (R,R)-(E,E) isomer as in HM-PAO

SHOW SMILES / InChI
Structure of TECHNETIUM TC-99M CYCLOBUTYL PROPYLENE AMINE OXIME

SMILES

O=[99Tc+3].C[C@@H]([N-]CC1(C[N-][C@H](C)C(\C)=N\[O-])CCC1)C(\C)=N\O

InChI

InChIKey=SYRDLYTYTQOQFZ-NQPMITLXSA-M
InChI=1S/C14H26N4O2.O.Tc/c1-10(12(3)17-19)15-8-14(6-5-7-14)9-16-11(2)13(4)18-20;;/h10-11,19-20H,5-9H2,1-4H3;;/q-2;;+3/p-1/b17-12+,18-13+;;/t10-,11-;;/m1../s1/i;;1+1

HIDE SMILES / InChI
Molecular Formula C14H26N4O2
Molecular Weight 282.3818
Charge -2
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 2
Optical Activity UNSPECIFIED
Molecular Formula OTc
Molecular Weight 114.9057
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

1973
98
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Approved
8429
OSTEOLITE

Approved Use

Unknown

Launch Date

1977
Diagnostic
Approved
8429
DRAXIMAGE MDP-10

Approved Use

MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis.

Launch Date

1978
PubMed

PubMed

TitleDatePubMed
Future of low specific activity molybdenum-99/technetium-99m generator.
2012 Oct
Patents

Patents

20050082469
43

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:37:17 GMT 2023
Edited
by admin
on Fri Dec 15 15:37:17 GMT 2023
Record UNII
JH18E0A8W1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TECHNETIUM TC-99M CYCLOBUTYL PROPYLENE AMINE OXIME
Common Name English
2-BUTANONE, 3,3'-(CYCLOBUTYLIDENEBIS(METHYLENEIMINO))BIS-, DIOXIME, TECHNETIUM-99 COMPLEX
Systematic Name English
TC-99M CB-PAO
Common Name English
TECHNETIUM-99TC, ((3,3'-(CYCLOBUTYLIDENEBIS(METHYLENEIMINO-.KAPPA.N))BIS(2-BUTANONE) DI(OXIMATO-.KAPPA.N))(3-))OXO-, (SP-5-15-(R*,R*))-
Systematic Name English
Code System Code Type Description
FDA UNII
JH18E0A8W1
Created by admin on Fri Dec 15 15:37:17 GMT 2023 , Edited by admin on Fri Dec 15 15:37:17 GMT 2023
PRIMARY
PUBCHEM
134160132
Created by admin on Fri Dec 15 15:37:17 GMT 2023 , Edited by admin on Fri Dec 15 15:37:17 GMT 2023
PRIMARY
CAS
131315-61-2
Created by admin on Fri Dec 15 15:37:17 GMT 2023 , Edited by admin on Fri Dec 15 15:37:17 GMT 2023
PRIMARY
Related Record Type Details
Structure of TECHNETIUM TC-99M
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of TECHNETIUM TC-99M
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