NORMEPERIDINE

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H19NO2
Molecular Weight	233.3062
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NORMEPERIDINE

SMILES

CCOC(=O)C1(CCNCC1)C2=CC=CC=C2

InChI

InChIKey=QKHMFBKXTNQCTM-UHFFFAOYSA-N

InChI=1S/C14H19NO2/c1-2-17-13(16)14(8-10-15-11-9-14)12-6-4-3-5-7-12/h3-7,15H,2,8-11H2,1H3

HIDE SMILES / InChI

Molecular Formula	C14H19NO2
Molecular Weight	233.3062
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Show entries

Title	Date	PubMed
Accumulation of normeperidine, an active metabolite of meperidine, in patients with renal failure of cancer.	1977 Jun	869353
Normeperidine toxicity.	1986 May	3963440
Norpethidine induced myoclonus in a patient with renal failure.	1989 Dec	2614458
CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.	2004 Sep	15319333
Seizures in an Alzheimer's disease patient as a complication of colonoscopy premedication with meperidine.	2008 Jan	17492380

Showing 1 to 5 of 5 entries

Patents

Substance Class	Chemical
Record UNII	JG096PMW2N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NORMEPERIDINE

Common Name

English

NSC-23821

Code

English

PETHIDINE-INTERMEDIATE-B, ETHYL-4-PHENYLPIPERIDINE-4-CARBOXYLATE

Common Name

English

IDS-NP-003

Code

English

ETHYL 4-PHENYLPIPERIDINE-4-CARBOXYLATE

Systematic Name

English

Showing 1 to 5 of 16 entries

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Classification Tree

Code System

Code

Sec. 1308.12 Schedule II.

DEA NO.

9233

Showing 1 to 1 of 1 entries

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Code System

Code

Type

Description

SMS_ID

100000088221

PRIMARY

ECHA (EC/EINECS)

201-008-9

PRIMARY

EPA CompTox

DTXSID50227806

PRIMARY

NSC

23821

PRIMARY

EVMPD

SUB21925

PRIMARY

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Related Record

Type

Details


					TZ9K6J4X8J

NORMEPERIDINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Comments:

APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)

Amount:

RELATIONSHIP_AMOUNT 86 (average)


					GT98GPM2FY

NORMEPERIDINE HYDROBROMIDE

SALT/SOLVATE -> PARENT

Comments:

APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)

Amount:

RELATIONSHIP_AMOUNT 74 (average)


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Amount:

44 % (average)

Showing 1 to 3 of 3 entries

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Related Record

Type

Details


					JG096PMW2N

ACTIVE MOIETY

Showing 1 to 1 of 1 entries

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC	[15 to 30] hours (average)