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GTPASE KRAS G12D MUTANT
JF12NT7SGW
Other
General
Record Details
Names
3
Identifiers
2
Subunits
1
Relationships
1
Characteristic Attributes
1
GTPASE KRAS G12D MUTANT
JF12NT7SGW
Other
General
Approval Year
Unknown
139,594
Record Details
Substance Class
Protein
Protein Type
SIGNAL TRANSDUCER (GTPASE)
Protein Sub Type
RAS
Sequence Origin
HUMAN
Sequence Type
COMPLETE
Record UNII
JF12NT7SGW
Record Status
Validated (UNII)
Record Version
17
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Names
3
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Name
Type
Language
Name
Type
Language
GTPASE KRAS G12D MUTANT
Common Name
English
KRAS G12D
Common Name
English
KRAS G12D PERSISTENTLY ACTIVE MUTANT
Common Name
English
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Identifiers
2
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Code System
Code
Type
Description
Code System
Code
Type
Description
UNIPROT
P01116
PRIMARY
FDA UNII
JF12NT7SGW
PRIMARY
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Related Record
Type
Details
Related Record
Type
Details
DU32DM9CHD
MRTX-1133
INHIBITOR -> TARGET
Comments:
pERK AGS assay
Qualification:
IC50
Amount:
2 NANOMOLAR (average)
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Characteristic Attributes
1
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Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
ESTIMATED 21200 Da (average)
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