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Details

Stereochemistry RACEMIC
Molecular Formula C21H23NO5S.C4H11NO3
Molecular Weight 522.611
Optical Activity ( + / - )
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SUDEXANOX TROMETHAMINE

SMILES

NC(CO)(CO)CO.CCCCCCC1=CC(=CC2=C1OC3=C(C=C(C=C3)C(O)=O)C2=O)S(C)(=N)=O

InChI

InChIKey=WANRNLFCCDCZPU-UHFFFAOYSA-N
InChI=1S/C21H23NO5S.C4H11NO3/c1-3-4-5-6-7-13-10-15(28(2,22)26)12-17-19(23)16-11-14(21(24)25)8-9-18(16)27-20(13)17;5-4(1-6,2-7)3-8/h8-12,22H,3-7H2,1-2H3,(H,24,25);6-8H,1-3,5H2

HIDE SMILES / InChI
Molecular Formula C21H23NO5S
Molecular Weight 401.476
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C4H11NO3
Molecular Weight 121.135
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Sudexanox is a xanthone derivative patented by French pharmaceutical company Roussel-UCLAF for the treatment of allergy, allergic asthma, and asthmatic bronchitis. In preclinical studies, Sudexanox possesses potent activity in the IgE-induced rat passive cutaneous anaphylaxis model.

Originator

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
High-performance liquid chromatographic method for the determination of sudexanox as the free acid in plasma.
1986-08-02
Patents

Patents

DE2530466
2
JP4746318B2
18
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:50:18 GMT 2025
Edited
by admin
on Mon Mar 31 21:50:18 GMT 2025
Record UNII
JBT8K7F1EG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RU 31 156
Preferred Name English
SUDEXANOX TROMETHAMINE
Common Name English
9H-XANTHENE-2-CARBOXYLIC ACID, 5-HEXYL-7-(S-METHYLSULFONIMIDOYL)-9-OXO-, COMPD. WITH 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL (1:1)
Systematic Name English
RU-31156
Code English
Code System Code Type Description
CAS
66934-53-0
Created by admin on Mon Mar 31 21:50:18 GMT 2025 , Edited by admin on Mon Mar 31 21:50:18 GMT 2025
PRIMARY
PUBCHEM
125649
Created by admin on Mon Mar 31 21:50:18 GMT 2025 , Edited by admin on Mon Mar 31 21:50:18 GMT 2025
PRIMARY
FDA UNII
JBT8K7F1EG
Created by admin on Mon Mar 31 21:50:18 GMT 2025 , Edited by admin on Mon Mar 31 21:50:18 GMT 2025
PRIMARY
EPA CompTox
DTXSID10985612
Created by admin on Mon Mar 31 21:50:18 GMT 2025 , Edited by admin on Mon Mar 31 21:50:18 GMT 2025
PRIMARY
Related Record Type Details
Structure of SUDEXANOX
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of SUDEXANOX
ACTIVE MOIETY
NIH
NCATS
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