SB-247853

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H19F3N4O2
Molecular Weight	428.4071
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=C(C=C2N(CCC2=C1)C(=O)NC3=CN=C(OCC4=CC=CC=N4)C=C3)C(F)(F)F

InChI

InChIKey=KLAHZRONIHBPPB-UHFFFAOYSA-N

InChI=1S/C22H19F3N4O2/c1-14-10-15-7-9-29(19(15)11-18(14)22(23,24)25)21(30)28-16-5-6-20(27-12-16)31-13-17-4-2-3-8-26-17/h2-6,8,10-12H,7,9,13H2,1H3,(H,28,30)

HIDE SMILES / InChI

Molecular Formula	C22H19F3N4O2
Molecular Weight	428.4071
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:40:37 GMT 2023` Edited by `admin` on `Sat Dec 16 01:40:37 GMT 2023`
Record UNII	JBJ4VCT98Y
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SB-247853

Code

English

5-METHYL-N-(6-(2-PYRIDYLMETHOXY)-3-PYRIDYL)-6-(TRIFLUOROMETHYL)INDOLINE-1-CARBOXAMIDE

Systematic Name

English

1H-INDOLE-1-CARBOXAMIDE, 2,3-DIHYDRO-5-METHYL-N-(6-(2-PYRIDINYLMETHOXY)-3-PYRIDINYL)-6-(TRIFLUOROMETHYL)-

Systematic Name

English

2,3-DIHYDRO-5-METHYL-N-(6-(2-PYRIDINYLMETHOXY)-3-PYRIDINYL)-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE

Systematic Name

English

SB247853

Code

English

Code System Code Type Description

CAS

200711-10-0

Created by admin on Sat Dec 16 01:40:37 GMT 2023 , Edited by admin on Sat Dec 16 01:40:37 GMT 2023

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FDA UNII

JBJ4VCT98Y

Created by admin on Sat Dec 16 01:40:37 GMT 2023 , Edited by admin on Sat Dec 16 01:40:37 GMT 2023

PRIMARY

PUBCHEM

9888804

Created by admin on Sat Dec 16 01:40:37 GMT 2023 , Edited by admin on Sat Dec 16 01:40:37 GMT 2023

PRIMARY

MANUFACTURER PRODUCT INFORMATION

SB-247853

Created by admin on Sat Dec 16 01:40:37 GMT 2023 , Edited by admin on Sat Dec 16 01:40:37 GMT 2023

PRIMARY

Related Record Type Details


					JBJ4VCT98Y

SB-247853

ACTIVE MOIETY

Comments:

SB-247853 is a highly specific 5-HT2c receptor antagonist. During the first dose-escalation study, 6 mg SB-247853 induced orthostatic intolerance in healthy volunteers.