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Details

Stereochemistry RACEMIC
Molecular Formula C17H19N
Molecular Weight 237.3395
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Tametraline, (+/-)-

SMILES

CN[C@@H]1CC[C@@H](C2=CC=CC=C2)C3=C1C=CC=C3

InChI

InChIKey=NVXPZMLRGBVYQV-WMLDXEAASA-N
InChI=1S/C17H19N/c1-18-17-12-11-14(13-7-3-2-4-8-13)15-9-5-6-10-16(15)17/h2-10,14,17-18H,11-12H2,1H3/t14-,17+/m0/s1

HIDE SMILES / InChI
Molecular Formula C17H19N
Molecular Weight 237.3395
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Tametraline (also known as CP-24,441) is a norepinephrine-dopamine reuptake inhibitor that was developed as an Antidepressant agent. Information about the current use of this drug is not available.

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins.
1984-11
Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain.
1976-12
Substance Class Chemical
Created
by admin
on Wed Apr 02 08:40:22 GMT 2025
Edited
by admin
on Wed Apr 02 08:40:22 GMT 2025
Record UNII
JAK4M6S8U3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CP 22186
Preferred Name English
Tametraline, (+/-)-
Common Name English
REL-(1R,4S)-1,2,3,4-TETRAHYDRO-N-METHYL-4-PHENYL-1-NAPHTHALENAMINE
Systematic Name English
1-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-N-METHYL-4-PHENYL-, TRANS-
Systematic Name English
1-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-N-METHYL-4-PHENYL-, (1R,4S)-REL-
Systematic Name English
CP-22,186
Code English
Code System Code Type Description
FDA UNII
JAK4M6S8U3
Created by admin on Wed Apr 02 08:40:22 GMT 2025 , Edited by admin on Wed Apr 02 08:40:22 GMT 2025
PRIMARY
CAS
52758-04-0
Created by admin on Wed Apr 02 08:40:22 GMT 2025 , Edited by admin on Wed Apr 02 08:40:22 GMT 2025
PRIMARY
NIH
NCATS
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