(3,4-Dichlorophenyl)methyl carbamimidothioate

NC(=N)SCC1=CC=C(Cl)C(Cl)=C1

InChIKey=LZTCFLDZLBOLDW-UHFFFAOYSA-N

InChI=1S/C8H8Cl2N2S/c9-6-2-1-5(3-7(6)10)4-13-8(11)12/h1-3H,4H2,(H3,11,12)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
rod shape-determining protein MreB (bacterial) 1 Target ID: rod shape-determining protein MreB (bacterial) Sources: https://www.ncbi.nlm.nih.gov/pubmed/27600765 \| https://www.ncbi.nlm.nih.gov/pubmed/19382805 \| https://www.ncbi.nlm.nih.gov/pubmed/27427089 \| https://www.ncbi.nlm.nih.gov/pubmed/28804018	Inhibitor 8504		1.32 µM [Kd]

PubMed

Title	Date	PubMed
Anti-biofilm activity of A22 ((S-3,4-dichlorobenzyl) isothiourea hydrochloride) against Pseudomonas aeruginosa: Influence on biofilm formation, motility and bioadhesion.	2017-10	28804018
Antibacterial, cyto and genotoxic activities of A22 compound ((S-3, 4 -dichlorobenzyl) isothiourea hydrochloride).	2016-10	27427089

Substance Class	Chemical Created by `admin` on `Wed Apr 02 05:22:09 GMT 2025` Edited by `admin` on `Wed Apr 02 05:22:09 GMT 2025`
Record UNII	J9ZA892FYX
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

(3,4-Dichlorophenyl)methyl carbamimidothioate

Systematic Name

English

S-(3,4-dichlorobenzyl) isothiourea

Preferred Name

English

A-22

Code

English

Carbamimidothioic acid, (3,4-dichlorophenyl)methyl ester

Systematic Name

English

[[(3,4-Dichlorophenyl)methyl]sulfanyl]methanimidamide

Systematic Name

English

Code System Code Type Description

FDA UNII

J9ZA892FYX