Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C43H49N7O10 |
| Molecular Weight | 823.8901 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC[C@H]1NC(=O)[C@@H](NC(=O)C2=C(O)C=CC=N2)[C@@H](C)OC(=O)[C@@H](NC(=O)[C@@H]3CC(=O)CCN3C(=O)[C@H](CC4=CC=CC=C4)N(C)C(=O)[C@@H]5CCCN5C1=O)C6=CC=CC=C6
InChI
InChIKey=FEPMHVLSLDOMQC-IYPFLVAKSA-N
InChI=1S/C43H49N7O10/c1-4-29-40(56)49-21-12-17-30(49)41(57)48(3)32(23-26-13-7-5-8-14-26)42(58)50-22-19-28(51)24-31(50)37(53)47-35(27-15-9-6-10-16-27)43(59)60-25(2)34(38(54)45-29)46-39(55)36-33(52)18-11-20-44-36/h5-11,13-16,18,20,25,29-32,34-35,52H,4,12,17,19,21-24H2,1-3H3,(H,45,54)(H,46,55)(H,47,53)/t25-,29-,30+,31+,32+,34+,35+/m1/s1
| Molecular Formula | C43H49N7O10 |
| Molecular Weight | 823.8901 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| A genetic time-delay circuitry in mammalian cells. | 2007-11-01 |
|
| Risk factors for acute generalized exanthematous pustulosis (AGEP)-results of a multinational case-control study (EuroSCAR). | 2007-11 |
|
| [Epidemiology of Haemophilus influenzae strains collected in 2004 in France and in vitro assessment of their susceptibility to antibiotics]. | 2007-06 |
|
| Patch testing for evaluating drug reactions due to systemic antibiotics. | 2007-06 |
|
| German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version). | 2007-06 |
|
| In vitro activities of 18 antimicrobial agents against Staphylococcus aureus isolates from the Institut Pasteur of Madagascar. | 2007-05-23 |
|
| Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution. | 2007-05-16 |
|
| Emergence of a Streptococcus pneumoniae isolate resistant to streptogramins by mutation in ribosomal protein L22 during pristinamycin therapy of pneumococcal pneumonia. | 2007-05 |
|
| Global distribution of Panton-Valentine leukocidin--positive methicillin-resistant Staphylococcus aureus, 2006. | 2007-04 |
|
| [Streptococcal impetigo at topical tacrolimus application sites in a woman with atopic dermatitis]. | 2007-03 |
|
| The potential role of concentrated animal feeding operations in infectious disease epidemics and antibiotic resistance. | 2007-02 |
|
| Characterisation of in vitro-selected mutants of Ureaplasma parvum resistant to macrolides and related antibiotics. | 2007-02 |
|
| Targeted Gene Disruption of the Cyclo (L-Phe, L-Pro) Biosynthetic Pathway in Streptomyces sp. US24 Strain. | 2007 |
|
| Improved production of pristinamycin coupled with an adsorbent resin in fermentation by Streptomyces pristinaespiralis. | 2006-11 |
|
| Adenoviral vector platform for transduction of constitutive and regulated tricistronic or triple-transcript transgene expression in mammalian cells and microtissues. | 2006-10 |
|
| Extensive cutaneous larva migrans with folliculitis mimicking multimetameric herpes zoster presentation in an adult traveler returning from Thailand. | 2006-08-04 |
|
| Pseudomonas aeruginosa otochondritis complicating localized cutaneous leishmaniasis: prevention of mutilation by early antibiotic therapy. | 2006-08 |
|
| Breakthrough pneumococcal meningitis in a patient treated with pristinamycin. | 2006-07 |
|
| [Antibiotherapy for acute CAP in adults]. | 2006-06-02 |
|
| [Tricuspid valve endocarditis after umbilical piercing]. | 2006-06 |
|
| Trends in the rates of resistance of Ureaplasma urealyticum to antibiotics and identification of the mutation site in the quinolone resistance-determining region in Chinese patients. | 2006-06 |
|
| [Acute community-acquired pneumonia. A review of clinical trials]. | 2006-05-19 |
|
| Emergence of a 23S rRNA mutation in Mycoplasma hominis associated with a loss of the intrinsic resistance to erythromycin and azithromycin. | 2006-04 |
|
| [Streptococcus agalactiae in nonpregnant adults]. | 2006-03 |
|
| Antibiotic resistance and mechanisms implicated in clinical enterococci in a Tunisian hospital. | 2006-02 |
|
| [Impetigo]. | 2006-02 |
|
| [Antibiotics resistance of meticilline-resistant Staphylococcus aureus: detection of the first glycopeptides low sensibility strains in Tunisia]. | 2006-02 |
|
| Occupational airborne contact dermatitis from pristinamycin. | 2006-01 |
|
| Resistance to macrolides, lincosamides, streptogramins, and linezolid among members of the Staphylococcus sciuri group. | 2006 |
|
| Prevalence and antibiotic susceptibility of genital Mycoplasma hominis and Ureaplasma urealyticum in a university hospital in Turkey. | 2006 |
|
| African tick-bite fever in French travelers. | 2005-11 |
|
| Granulomatous mastitis and corynebacteria: clinical and pathologic correlations. | 2005-09-22 |
|
| Correlation of agar dilution and VITEK2 system for detection of resistance to macrolides, lincosamides and pristinamycin among Staphylococcus aureus and Staphylococcus epidermidis: association with genotypes. | 2005-08 |
|
| [Efficacy and safety of pristinamycin vs amoxicillin in community acquired pneumonia in adults]. | 2005-07-08 |
|
| Chemoenzymatic approach to enantiopure streptogramin B variants: characterization of stereoselective pristinamycin I cyclase from Streptomyces pristinaespiralis. | 2005-07-06 |
|
| [Enterococcal bacteremia at Nîmes university hospital]. | 2005-06-15 |
|
| Successful oral pristinamycin therapy for osteoarticular infections due to methicillin-resistant Staphylococcus aureus (MRSA) and other Staphylococcus spp. | 2005-06 |
|
| Efficacy and safety of telithromycin 800 mg once daily for 7 days in community-acquired pneumonia: an open-label, multicenter study. | 2005-05-31 |
|
| The TyrA family of aromatic-pathway dehydrogenases in phylogenetic context. | 2005-05-12 |
|
| Clonal comparison of Staphylococcus aureus isolates from healthy pig farmers, human controls, and pigs. | 2005-05 |
|
| Fatal pristinamycin-induced toxic epidermal necrolysis (Lyell's syndrome): difficulties in attributing causal association in the polymedicated intensive care unit patient. | 2005-05 |
|
| Susceptibility of methicillin-resistant Staphylococcus aureus to vancomycin, teicoplanin, linezolid, pristinamycin and other antibiotics. | 2005-03 |
|
| Antimicrobial susceptibility of bifidobacteria. | 2005-01 |
|
| Cloxacillin versus pristinamycin for superficial pyodermas: a randomized, open-label, non-inferiority study. | 2005 |
|
| Beta-haemolytic streptococci in acute pharyngitis. | 2004-11-26 |
|
| Solvent affects the conformation of virginiamycin M1 (pristinamycin IIA, streptogramin A). | 2004-10-21 |
|
| [Efficiency of a four-day course of pristinamycin compared to a five-day course of cefuroxime axetil for acute bacterial maxillary sinusitis in adult outpatients]. | 2004-07 |
|
| Impact of susceptibility to antibiotics of streptococci & enterococci isolated from patients with infective endocarditis on antibiotic treatment. | 2004-05 |
|
| Antimicrobial resistance in commensal flora of pig farmers. | 2004-05 |
|
| [Treatment of exacerbations of chronic obstructive pulmonary disease with pristinamycin]. | 2004-04 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 17:58:27 GMT 2025
by
admin
on
Mon Mar 31 17:58:27 GMT 2025
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| Record UNII |
J91D5GN5AT
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| Record Status |
Validated (UNII)
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| Record Version |
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NCI_THESAURUS |
C937
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VIRGINIAMYCIN S1
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DTXSID0046856
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23152-29-6
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C1296
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m11470
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J91D5GN5AT
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DB04805
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5388936
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177858
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46416
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245-462-6
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CHEMBL1236684
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