POTASSIUM SILICATE

First marketed in 1921

Details

Stereochemistry	ACHIRAL
Molecular Formula	2K.O5Si2
Molecular Weight	214.3646
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[K+].[K+].[O-][Si](=O)O[Si]([O-])=O

InChI

InChIKey=QQUPHDGGHUDUKR-UHFFFAOYSA-N

InChI=1S/2K.O5Si2/c;;1-6(2)5-7(3)4/q2*+1;-2

HIDE SMILES / InChI

Molecular Formula	O5Si2
Molecular Weight	136.168
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	K
Molecular Weight	39.0983
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/29764543 | https://www.mayoclinic.org/drugs-supplements/potassium-supplement-oral-route-parenteral-route/description/drg-20070753 | https://www.ncbi.nlm.nih.gov/pubmed/28419159

Potassium is needed to maintain good health. When potassium level falls below 3.5 mmol/L, Hypokalemia is diagnosed. In case of extremely low level of potassium (lower than 2.5 mmol/L) the following symptoms are appeared: malaise and fatigue. This low level of potassium can lead to severe muscle weakness and paralysis; respiratory failure; intermittent muscle spasms. It is known, foods that are good sources of potassium and low in sodium may reduce the risk of high blood pressure and stroke. Potassium supplementation is also recommended as an adjuvant antihypertensive agent for patients with essential hypertension.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
essential hypertension 13 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28419159	Palliative		Phase III 656	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
		96279836
Mineral and water nutrition.	1991 Jul	1893277
Diet, genetics and hypertension.	1997 Aug	9263178
Inhibition of HIV-1 infection by zinc group metal compounds.	1999 Sep	10517314
Delay of natural bone loss by higher intakes of specific minerals and vitamins.	2001 May	11401244
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.	2003 Feb 14	12559919

Patents

Sample Use Guides

In Vivo Use Guide

Potassium is administered in various dosage forms (gluconate, citrate, chloride, bicarbonate). Exact dose should be determined by a doctor. Most people will not take more than 100 mEq a day.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:39:30 UTC 2023` Edited by `admin` on `Fri Dec 15 16:39:30 UTC 2023`
Record UNII	J86L1GUL6K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

POTASSIUM SILICATE

Official Name

English

POTASSIUM SILICATE [MI]

Common Name

English

POTASSIUM POLYSILICATE [HSDB]

Common Name

English

KALI SILICATUM

Common Name

English

POTASSIUM SILICATE [INCI]

Common Name

English

POTASSIUM POLYSILICATE

Common Name

English

SOLUBLE POTASH GLASS

Common Name

English

SILICIC ACID POTASSIUM SALT

Common Name

English

SOLUBLE POTASH WATER GLASS

Common Name

English

KALI SILICATUM [HPUS]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

72606