Details
Stereochemistry | ACHIRAL |
Molecular Formula | C14H9ClF2N2O2 |
Molecular Weight | 310.683 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
FC1=CC=CC(F)=C1C(=O)NC(=O)NC2=CC=C(Cl)C=C2
InChI
InChIKey=QQQYTWIFVNKMRW-UHFFFAOYSA-N
InChI=1S/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)
Molecular Formula | C14H9ClF2N2O2 |
Molecular Weight | 310.683 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Diflubenzuron is a direct-acting insecticide normally applied directly to plants or water. Diflubenzuron, besides its use in agriculture, horticulture and forestry against larvae of Lepidoptera, Coleoptera, Diptera, Hymenoptera, and in public health against larvae of mosquitoes, is used as a veterinary drug for the treatment of sea lice infestations in Atlantic salmon. Diflubenzuron acts by interference with the synthesis of chitin. It is reported that public exposure to diflubenzuron through either food or drinking-water is negligible.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: CHEMBL613468 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21268527 |
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Target ID: Sulfonylurea receptor of Blattella germanica |
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Target ID: GO:0006031 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15262279 |
65.0 nM [Kd] |
PubMed
Title | Date | PubMed |
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Effects of diflubenzuron on growth and glutathione in mosquito fish (Gambusia affinis). | 2001 |
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Cabbage root fly control using non-organophosphorus insecticides. | 2001 |
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Bait matrix for delivery of chitin synthesis inhibitors to the formosan subterranean termite (Isoptera: Rhinotermitidae). | 2001 Apr |
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Inheritance of diflubenzuron resistance and monooxygenase activities in a laboratory-selected strain of Lucilia cuprina (Diptera: Calliphoridae). | 2001 Oct |
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Effect of diflubenzuron on immature stages of Haematobia irritans (L.) (Diptera: Muscidae) in Uberlândia, State of Minas Gerais, Brazil. | 2002 Jul |
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Effects of common-use pesticides on developmental and reproductive processes in Daphnia. | 2002 Jun |
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Significance of penetration, excretion, and transovarial uptake to toxicity of three insect growth regulators in predatory lacewing adults. | 2002 Oct |
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Age-dependent response to insecticides and enzymatic variation in susceptible and resistant codling moth larvae. | 2002 Oct |
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Methoxyfenozide, a reliable IPM compatible compound against Lepidoptera in pome fruit and vegetables with sterilising, ovicidal and larvicidal efficacy on codling moth. | 2003 |
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Laboratory and field evaluation of tebufenozide, diflubenzuron, and Bacillus thurengiensis var. kurstaki for suppression of Douglas-fir tussock moth (Orgyia pseudotsugata (McDunnough)) in Idaho: a case study. | 2003 Apr |
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Horizontal and trophic transfer of diflubenzuron and fipronil among grasshoppers (Melanoplus sanguinipes) and between grasshoppers and darkling beetles (Tenebrionidae). | 2003 Apr |
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Toxicity and pharmacokinetics of insect growth regulators and other novel insecticides on pupae of Hyposoter didmator (Hymenoptera: Ichneumonidae), a parasitoid of early larval instars of lepidopteran pests. | 2003 Aug |
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Constraints on adaptive mutations in the codling moth Cydia pomonella (L.): measuring fitness trade-offs and natural selection. | 2003 Jan |
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Effects of boric acid, fipronil, hydramethylnon, and diflubenzuron baits on colonies of ghost ants (Hymenoptera: Formicidae). | 2003 Jun |
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Cytotoxic effects of two antimolting insecticides in mammalian CHO-K1 cells. | 2003 May |
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Benzoylphenylurea residues in peppers and zucchinis grown in greenhouses: determination of decline times and pre-harvest intervals by modelling. | 2004 Feb |
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Effectiveness of twelve insecticides applied topically to diapausing larvae of the codling moth, Cydia pomonella L. | 2004 Mar |
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[Evaluation of the inhibiting activity of the diflubenzuron on the ecdysis of larvae of Aedes aegypti (Linnaeus, 1762) (Diptera, Culicidae)]. | 2004 Mar-Apr |
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Effect of temperature on efficacy of insecticides to differential grasshopper (Orthoptera: Acrididae). | 2004 Oct |
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The effects of four insect growth-regulating (IGR) insecticides on honeybee (Apis mellifera L.) colony development, queen rearing and drone sperm production. | 2005 Oct |
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Fragmentation study and analysis of benzoylurea insecticides and their analogs by liquid chromatography-electrospray ionization-mass spectrometry. | 2006 Aug 15 |
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[An outbreak of Plasmodium vivax malaria in Kyrghyzstan]. | 2006 Jan-Mar |
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Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
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Characterization of a chitin synthase cDNA and its increased mRNA level associated with decreased chitin synthesis in Anopheles quadrimaculatus exposed to diflubenzuron. | 2006 Sep |
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Simulated field evaluation of the efficacy of two formulations of diflubenzuron, a chitin synthesis inhibitor against larvae of Aedes aegypti (L.) (Diptera: Culicidae) in water-storage containers. | 2007 Mar |
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New method for the photo-chemiluminometric determination of benzoylurea insecticides based on acetonitrile chemiluminescence. | 2007 Mar |
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Diversity of insecticide resistance mechanisms and spectrum in European populations of the codling moth, Cydia pomonella. | 2007 Sep |
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Efficacy results of insecticides against Cydia pomonella, the codling moth, in Belgium during the last decade (1998-2007). | 2008 |
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Pharmacogenetic and metabolic differences between dog breeds: their impact on canine medicine and the use of the dog as a preclinical animal model. | 2008 |
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Field evaluation of the bioefficacy of diflubenzuron (Dimilin) against container-breeding Aedes sp. mosquitoes. | 2008 Apr |
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Determination of photoirradiated high polar benzoylureas in tomato by HPLC with luminol chemiluminescence detection. | 2008 Aug 15 |
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Resistance to benzoylphenyl urea insecticides in Australian populations of the sheep body louse. | 2008 Dec |
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Resistance to insect growth regulator insecticides in populations of sheep lice as assessed by a moulting disruption assay. | 2008 Dec |
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Availability of insecticidal molecules to control Aedes albopictus (Skuse). | 2008 Jun |
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Chitin in the peritrophic membrane of Acarus siro (Acari: Acaridae) as a target for novel acaricides. | 2008 Jun |
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[Simultaneous determination of diflubenzuron and triflumuron residues in greasy wool using high performance liquid chromatography]. | 2008 Nov |
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Effectiveness of pyriproxyfen and diflubenzuron formulations as larvicides against Aedes aegypti. | 2008 Sep |
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Acute effects of diflubenzuron on the freshwater fish Prochilodus lineatus. | 2008 Sep |
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Molecular phylogeny and population structure of the codling moth (Cydia pomonella) in Central Europe: I. Ancient clade splitting revealed by mitochondrial haplotype markers. | 2008 Sep |
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Chitinase is stored and secreted from the inner body of microfilariae and has a role in exsheathment in the parasitic nematode Brugia malayi. | 2008 Sep |
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A method for eradicating amphipod parasites (hyperiidae) from host jellyfish, Chrysaora fuscescens (Brandt, 1835), in a closed recirculating system. | 2009 Mar |
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Effects of benzoylphenylurea on chitin synthesis and orientation in the cuticle of the Drosophila larva. | 2009 Mar |
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 17:13:05 GMT 2023
by
admin
on
Fri Dec 15 17:13:05 GMT 2023
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Record UNII |
J76U6ZSI8D
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Record Status |
Validated (UNII)
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Record Version |
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WHO-VATC |
QP53BC02
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EPA PESTICIDE CODE |
108201
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m4431
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