TETRAMETHYLTHIOUREA

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H12N2S
Molecular Weight	132.227
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)C(=S)N(C)C

InChI

InChIKey=MNOILHPDHOHILI-UHFFFAOYSA-N

InChI=1S/C5H12N2S/c1-6(2)5(8)7(3)4/h1-4H3

HIDE SMILES / InChI

Molecular Formula	C5H12N2S
Molecular Weight	132.227
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Dicyanidobis(N,N'-dimethythio-urea-κS)mercury(II).	2010-08-04	21588485
Dicyanidobis(thio-urea-κS)cadmium(II) monohydrate.	2010-07-24	21588216
Dichloridobis(N,N,N',N'-tetra-methyl-thio-urea-κS)mercury(II).	2010-07-17	21588182
Diiodidobis(N,N,N',N'-tetra-methyl-thio-urea-κS)cadmium(II).	2010-07-17	21588181
Dibromidobis(N,N,N',N'-tetra-methyl-thio-urea-κS)cadmium(II).	2010-07-17	21588180
Tuning the reactivity of chelated dinuclear Pt(II) complexes through a flexible diamine linker. A detailed kinetic and mechanistic study.	2010-04-21	20354613
Platinum(II) mediated C(sp3)-H activation of tetramethylthiourea.	2009-10-14	19771375
Mixed adsorption layers of 0.1 M tert-butanol-tetramethylthiourea at the interface of Hg/aqueous perchlorate solutions.	2009-04-15	19185313
Controlling the extent of pi-backbonding in platinum(ii) terpyridyl systems: a detailed kinetic, mechanistic and computational approach.	2008-12-21	19153620
DNA-binding activity of NF-kappaB and phosphorylation of p65 are induced by N-acetylcysteine through phosphatidylinositol (PI) 3-kinase.	2008-09	18657320
Effect of sodium sulfite on mast cell degranulation and oxidant stress.	2006-04	16680925
Studies on the goitrogenic mechanism of action of N,N,N',N'-tetramethylthiourea.	2006-01-16	16297522
Structural modifications of aqueous ionic micelles in the presence of denaturants as studied by DLS and viscometry.	2005-10-11	16207020
Air pollution particles activate NF-kappaB on contact with airway epithelial cell surfaces.	2005-10-01	16164960
Transforming growth factor-beta1 drives airway remodeling in cigarette smoke-exposed tracheal explants.	2005-10	15994428
Use of a stopped-flow technique for investigation and determination of thiourea and its N-methyl derivatives as inducers of the iodine-azide reaction.	2005-08	15997371
Tetramethyl thiourea/Co2(CO)8-catalyzed Pauson-Khand reaction under balloon pressure of CO.	2005-02-17	15704902
An electrochemical quartz crystal microbalance study of the etching of gold surfaces in the presence of tetramethylthiourea.	2004-11-01	15380425
Role of chelate substituents and cis sigma-effect on the rate of ligand substitution at Pt(N-N-N) and Pt(N-N-C) centres.	2004-01-21	15356727
Cigarette smoke produces airway wall remodeling in rat tracheal explants.	2003-11-15	12958058
Cyclometalated analogues of platinum terpyridine complexes: kinetic study of the strong sigma-donor cis and trans effects of carbon in the presence of a pi-acceptor ligand backbone.	2003-10-06	14514330
Air pollution particles produce airway wall remodeling in rat tracheal explants.	2003-09	12649123
Redox regulation of HIF-1alpha levels and HO-1 expression in renal medullary interstitial cells.	2003-06	12595275
Synthesis of the P-cluster inorganic core of nitrogenases.	2003-04-09	12670218
Chalcogenide-Lewis acid mediated reactions of electron-deficient alkynes with aldehydes.	2003-04-04	12658646
Electronic tuning of the lability of Pt(II) complexes through pi-acceptor effects. Correlations between thermodynamic, kinetic, and theoretical parameters.	2003-03-10	12611540
Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate.	2002-12-30	12495358
In vitro and in vivo activation of extracellular signal-regulated kinases by coal dusts and quartz silica.	2002-10-01	12392967
Iron loading makes a nonfibrogenic model air pollutant particle fibrogenic in rat tracheal explants.	2002-06	12034567
Cadmium-induced apoptosis of primary epithelial lung cells: involvement of Bax and p53, but not of oxidative stress.	2002	11991084
Synthesis and characterization of the dimercury(I)-linked compound [PPn]4[(Re7C(CO)21Hg)2]. Oxidative cleavage of the mercury-mercury bond leading to carbidoheptarhenate complexes of mercury(II), including [PPN][Re7C(CO)21Hg(S=C(NME2)2)].	2001-09-10	11531437
Relationship of fiber surface iron and active oxygen species to expression of procollagen, PDGF-A, and TGF-beta(1) in tracheal explants exposed to amosite asbestos.	2001-04	11306436
Silica-induced activation of c-Jun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress.	2001-03-01	11280724
Receptor mediated endocytosis by mesangial cells modulates transmigration of macrophages.	2000-12	11128050
Effects of pro- and antioxidative compounds on renal production of erythropoietin.	1999-02	9927288
Thioureas differentially induce rat hepatic microsomal epoxide hydrolase and rGSTA2 irrespective of their oxygen radical scavenging effect: effects on toxicant-induced liver injury.	1999-01-29	10190572
Toxic metals stimulate inflammatory cytokines in hepatocytes through oxidative stress mechanisms.	1998-08	9707512
Anthralin stimulates keratinocyte-derived proinflammatory cytokines via generation of reactive oxygen species.	1998-04	9628260
Regulation of RANTES and ICAM-1 expression in murine mesangial cells.	1997-04	10495789
Induction of heparin-binding epidermal growth factor-like growth factor mRNA in rat kidney after acute injury.	1995-08	7635938

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:47:31 GMT 2025` Edited by `admin` on `Mon Mar 31 18:47:31 GMT 2025`
Record UNII	J6T67A1P72
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TETRAMETHYLTHIOUREA

Systematic Name

English

NSC-102499

Preferred Name

English

1,1,3,3-TETRAMETHYL-2-THIOUREA

Systematic Name

English

TETRAMETHYL-2-THIOUREA, 1,1,3,3-

Systematic Name

English

TETRAMETHYLTHIOUREA [HSDB]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID5026126