Zirconium Zr-89 Crefmirlimab Berdoxam

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 01:59:52 GMT 2025` Edited by `admin` on `Wed Apr 02 01:59:52 GMT 2025`
Protein Type	MINIBODY
Protein Sub Type
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	J6AJI0OZ1O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Zirconium Zr-89 Crefmirlimab Berdoxam

Official Name

English

Zirconium (89Zr) Crefmirlimab Berdoxam

Preferred Name

English

ZIRCONIUM ZR 89 CREFMIRLIMAB BERDOXAM [USAN]

Common Name

English

IMMUNOGLOBULIN, ANTI-(HUMAN CD8A ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IAB22M2C .KAPPA.-CHAIN V-J REGION) FUSION PROTEIN WITH PEPTIDE LINKER (GSTSGGGSGGGSGGGGSS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD8A ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONA

Common Name

English

IAB22M2C (ANTIBODY FRAGMENT AGAINST THE HUMAN CD8-ANTIGEN ON CD8-POSITIVE T-CELLS, CONJUGATED TO THE CHELATOR DESFERRIOXAMINE (DF) AND LABELED WITH THE RADIOISOTOPE ZIRCONIUM ZR-89)

Common Name

English

ZIRCONIUM ZR-89-DESFERRIOXAMINE-IAB22M2C

Common Name

English

zirconium (??Zr) crefmirlimab berdoxam [INN]

Common Name

English

ZIRCONIUM ZR 89-DF-IAB22M2C

Common Name

English

89ZRDFIAB22M2C

Code

English

89ZR-DF-IAB22M2C

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C1511

Created by admin on Wed Apr 02 01:59:52 GMT 2025 , Edited by admin on Wed Apr 02 01:59:52 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C137822

Created by admin on Wed Apr 02 01:59:52 GMT 2025 , Edited by admin on Wed Apr 02 01:59:52 GMT 2025

PRIMARY

NCIT

INN

12138

Created by admin on Wed Apr 02 01:59:52 GMT 2025 , Edited by admin on Wed Apr 02 01:59:52 GMT 2025

PRIMARY

USAN

JK-118

Created by admin on Wed Apr 02 01:59:52 GMT 2025 , Edited by admin on Wed Apr 02 01:59:52 GMT 2025

PRIMARY

CAS

2377668-38-5

Created by admin on Wed Apr 02 01:59:52 GMT 2025 , Edited by admin on Wed Apr 02 01:59:52 GMT 2025

PRIMARY

SMS_ID

300000026117

Created by admin on Wed Apr 02 01:59:52 GMT 2025 , Edited by admin on Wed Apr 02 01:59:52 GMT 2025

PRIMARY

FDA UNII

J6AJI0OZ1O

Created by admin on Wed Apr 02 01:59:52 GMT 2025 , Edited by admin on Wed Apr 02 01:59:52 GMT 2025

PRIMARY

From	To
1_23	1_88
1_147	1_221
1_254	2_254
1_257	2_257
1_260	2_260
1_297	1_355
2_23	2_88
2_147	2_221
2_297	2_355

Related Record Type Details


					2946IE3VYD

CD8

TARGET->RADIOLIGAND

Amount:


					PTO7SXB9L7

NON-LABELED -> LABELED

Amount:


					AB3OGA5ZFL

LYSINE, N6-(P-DITHIOUREA-PHENYL-DEFEROXAMINE)

CONJUGATE COMPONENT->CONJUGATE

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION		RESIDUE_SPECIFIC		Amount:	LYSINE, N6-(P-DITHIOUREA-PHENYL-DEFEROXAMINE)	AB3OGA5ZFL
MOIETY		CHELATOR		Amount:	ZIRCONIUM CATION ZR-89	S73W82W0KO

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL