Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Wed Apr 02 01:28:21 GMT 2025
by
admin
on
Wed Apr 02 01:28:21 GMT 2025
|
| Protein Type | GROWTH FACTOR |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
J4PM6GL09E
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
J4PM6GL09E
Created by
admin on Wed Apr 02 01:28:21 GMT 2025 , Edited by admin on Wed Apr 02 01:28:21 GMT 2025
|
PRIMARY | |||
|
O14944
Created by
admin on Wed Apr 02 01:28:21 GMT 2025 , Edited by admin on Wed Apr 02 01:28:21 GMT 2025
|
PRIMARY |
| From | To |
|---|---|
| 1_6 | 1_19 |
| 1_14 | 1_30 |
| 1_32 | 1_41 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
INHIBITOR -> TARGET |
Binds to key residues in the C?terminal regions of TGF?? and epiregulin, preventing their binding to the EGFR. Engagement of the 2 targets by LY results in internalization of the transmembrane precursors and neutralization of the activity of the mature ligands in vitro.
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|