U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
17.44 nM [Ki]
PubMed

PubMed

TitleDatePubMed
The galanin-3 receptor antagonist, SNAP 37889, reduces operant responding for ethanol in alcohol-preferring rats.
2011-01-17
Involvement of galanin receptors 1 and 2 in the modulation of mouse vagal afferent mechanosensitivity.
2007-09-01
Amino substituted analogs of 1-phenyl-3-phenylimino-2-indolones with potent galanin Gal3 receptor binding affinity and improved solubility.
2006-08-01
3-arylimino-2-indolones are potent and selective galanin GAL3 receptor antagonists.
2006-06-29
Galanin receptor antagonists : a potential novel pharmacological treatment for mood disorders.
2006
Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299.
2005-11-29
Substance Class Mixture
Created
by admin
on Tue Apr 01 21:44:11 GMT 2025
Edited
by admin
on Tue Apr 01 21:44:11 GMT 2025
Record UNII
J4DRJ9BFS1
Record Status Validated (UNII)
Record Version
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Name Type Language
HT-2157
Code English
SNAP-37889
Preferred Name English
1,3-DIHYDRO-1-PHENYL-3-((3-(TRIFLUOROMETHYL)PHENYL)IMINO)-2H-INDOL-2-ONE
Systematic Name English
1-PHENYL-3-((3-(TRIFLUOROMETHYL)PHENYL)IMINO)-1,3-DIHYDRO-2H-INDOL-2-ONE
Systematic Name English
2H-INDOL-2-ONE, 1,3-DIHYDRO-1-PHENYL-3-((3-(TRIFLUOROMETHYL)PHENYL)IMINO)-
Systematic Name English
Code System Code Type Description
FDA UNII
J4DRJ9BFS1
Created by admin on Tue Apr 01 21:44:11 GMT 2025 , Edited by admin on Tue Apr 01 21:44:11 GMT 2025
PRIMARY
CAS
303149-14-6
Created by admin on Tue Apr 01 21:44:11 GMT 2025 , Edited by admin on Tue Apr 01 21:44:11 GMT 2025
PRIMARY
WIKIPEDIA
HT-2157
Created by admin on Tue Apr 01 21:44:11 GMT 2025 , Edited by admin on Tue Apr 01 21:44:11 GMT 2025
PRIMARY
EPA CompTox
DTXSID701032019
Created by admin on Tue Apr 01 21:44:11 GMT 2025 , Edited by admin on Tue Apr 01 21:44:11 GMT 2025
PRIMARY
Any of these components may be present:
Definition References