DAPIGLUTIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 07:26:35 GMT 2025` Edited by `admin` on `Wed Apr 02 07:26:35 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	J43GMI6IYW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

dapiglutide [INN]

Preferred Name

English

DAPIGLUTIDE

Official Name

English

L-ASPARTIC ACID, L-HISTIDYL-2-METHYLALANYL-L-.ALPHA.-GLUTAMYLGLYCYL-L-SERYL-L-PHENYLALANYL-L-THREONYL-L-SERYL-L-.ALPHA.-GLUTAMYL-L-LEUCYL-L-ALANYL-L-THREONYL-L-ISOLEUCYL-L-LEUCYL-L-.ALPHA.-ASPARTYL-N6-(N-(17-CARBOXY-1-OXOHEPTADECYL)-L-.GAMMA.-GLUTAMYL)-L

Common Name

English

HUMAN GLUCAGON LIKE PEPTIDE-2 (GLP-2) ANALOGUE; N6.16-(N-(17-CARBOXYHEPTADECANOYL)-L-.GAMMA.-GLUTAMYL)- (A2>AIB (2-METHYLALANINE), D3>E, S7>T, D8>S, M10>L, N11>A, N16>K, L17>Q, N24>A, T29>H)HUMAN GLUCAGONLIKE PEPTIDE 2 (GLP-2)

Common Name

English

Code System Code Type Description

INN

11396

Created by admin on Wed Apr 02 07:26:35 GMT 2025 , Edited by admin on Wed Apr 02 07:26:35 GMT 2025

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CAS

2296814-85-0

Created by admin on Wed Apr 02 07:26:35 GMT 2025 , Edited by admin on Wed Apr 02 07:26:35 GMT 2025

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SMS_ID

300000018719

Created by admin on Wed Apr 02 07:26:35 GMT 2025 , Edited by admin on Wed Apr 02 07:26:35 GMT 2025

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FDA UNII

J43GMI6IYW

Created by admin on Wed Apr 02 07:26:35 GMT 2025 , Edited by admin on Wed Apr 02 07:26:35 GMT 2025

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NCI_THESAURUS

C175764

Created by admin on Wed Apr 02 07:26:35 GMT 2025 , Edited by admin on Wed Apr 02 07:26:35 GMT 2025

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Related Record Type Details


					EF38T7N5MI

GLUCAGON-LIKE PEPTIDE 1 RECEPTOR

TARGET -> AGONIST

Amount:


					I22705MV2H

GLUCAGON-LIKE PEPTIDE 2 RECEPTOR

TARGET -> AGONIST

Amount:

Related Record Type Details


					J43GMI6IYW

ACTIVE MOIETY

Comments:

Glucagon like peptides (GLP) analogue

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_2]	SITE_SPECIFIC			.ALPHA.-AMINOISOBUTYRIC ACID	1E7ZW41IQU
AMINO_ACID_SUBSTITUTION	[1_16]	SITE_SPECIFIC			N6-(17-CARBOXYHEPTADECANOYL-GAMMA-GLU)-LYSINE	G83QQ34CE4

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER AVERAGE	CHEMICAL