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Details

Stereochemistry RACEMIC
Molecular Formula C14H14O2S
Molecular Weight 246.325
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IDPH-8261

SMILES

COC(=O)C(C)C1=CC=C(C=C1)C2=CSC=C2

InChI

InChIKey=WINXAKJYORVNHU-UHFFFAOYSA-N
InChI=1S/C14H14O2S/c1-10(14(15)16-2)11-3-5-12(6-4-11)13-7-8-17-9-13/h3-10H,1-2H3

HIDE SMILES / InChI

Molecular Formula C14H14O2S
Molecular Weight 246.325
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Atliprofen (previously known as IDPH 8261), a nonsteroidal anti-inflammatory cyclooxygenase inhibitor was developed as an anti-inflammatory drug. Low toxicity and high efficacy allowed making this compound a potentially useful therapeutic agent. IDPH 8261 participated in the clinical trial phase III in India for the treatment of rheumatic disorders However, information about the further development of the drug is not available.

Approval Year

PubMed

PubMed

TitleDatePubMed
Synthesis and evaluation of S-4-(3-thienyl)phenyl-alpha-methylacetic acid.
2004-02-23
IDPH-8261--a new nonsteroidal antiinflammatory agent.
1995-01
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 22:22:57 GMT 2025
Edited
by admin
on Mon Mar 31 22:22:57 GMT 2025
Record UNII
J4387865F3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ATLIPROFEN METHYL ESTER
Preferred Name English
IDPH-8261
Common Name English
BENZENEACETIC ACID, .ALPHA.-METHYL-4-(3-THIENYL)-, METHYL ESTER
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID60869498
Created by admin on Mon Mar 31 22:22:57 GMT 2025 , Edited by admin on Mon Mar 31 22:22:57 GMT 2025
PRIMARY
CAS
108912-17-0
Created by admin on Mon Mar 31 22:22:57 GMT 2025 , Edited by admin on Mon Mar 31 22:22:57 GMT 2025
PRIMARY
FDA UNII
J4387865F3
Created by admin on Mon Mar 31 22:22:57 GMT 2025 , Edited by admin on Mon Mar 31 22:22:57 GMT 2025
PRIMARY
PUBCHEM
130978
Created by admin on Mon Mar 31 22:22:57 GMT 2025 , Edited by admin on Mon Mar 31 22:22:57 GMT 2025
PRIMARY
Related Record Type Details
ACTIVE MOIETY