DISODIUM SEBACATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H16O4.2Na
Molecular Weight	246.2112
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[Na+].[O-]C(=O)CCCCCCCCC([O-])=O

InChI

InChIKey=NCXUIEDQTCQZRK-UHFFFAOYSA-L

InChI=1S/C10H18O4.2Na/c11-9(12)7-5-3-1-2-4-6-8-10(13)14;;/h1-8H2,(H,11,12)(H,13,14);;/q;2*+1/p-2

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C10H16O4
Molecular Weight	200.2316
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Acne 98 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=79f8fc90-2447-4224-ac79-1645d1c82d4f	Inactive ingredient		Approved 8429	KLEER-PLEX ADVANCED ACNE CARE SYSTEM Approved Use Acne Treatment. - For the management of acne. - Clears up most acne pimples, blackheads, and whiteheads and allows skin to heal. - Penetrates pores to eliminate most acne blemishes. - Helps prevent new acne pimples.

PubMed

Title	Date	PubMed
C6-C10-dicarboxylic aciduria: biochemical considerations in relation to diagnosis of beta-oxidation defects.	1982	6959231
Prenatal diagnosis of glutaric aciduria type II by direct chemical analysis of dicarboxylic acids in amniotic fluid.	1984 Jan	6698061
Inhibition of HIV-1 proteinase by non-peptide carboxylates.	1991 Apr 15	2018518
Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.	1991 Jan 2	2026685
Use of even-numbered carbon atom dicarboxylic salts in parenteral nutrition as fuel substrate.	1992 Jan-Feb	1738216
Sebacic acid binding to human plasma albumin.	1993 Feb 9	8442769
A new HPLC method for the direct analysis of triglycerides of dicarboxylic acids in biological samples.	1999 Nov	10556649
The lock-in phase in the urotropine-sebacic acid system.	2001 Aug	11498619
Urinary organic acids in peroxisomal disorders: a simple screening method.	2001 Jul 5	11482738
In vitro fibrillogenesis of the amyloid beta 1-42 peptide: cholesterol potentiation and aspirin inhibition.	2002	12475558
Pharmacokinetics of the carmustine implant.	2002	12074689
Application of TPX polymer membranes for the controlled release of triprolidine.	2002 Jan 31	11790496
Carbohydrate, glycolipid, and lipid components from the photobiont (Scytonema sp.) of the lichen, Dictyomema glabratum.	2005 Aug 15	15963960
A new potentiometric ammonium electrode for biosensor construction.	2006	16893815
Poly(glycerol sebacate) supports the proliferation and phenotypic protein expression of primary baboon vascular cells.	2007 Dec 15	17584900
Effects of insemination quantity on honey bee queen physiology.	2007 Oct 3	17912357
Structural characterization of synthetic poly(ester amide) from sebacic acid and 4-amino-1-butanol by matrix-assisted laser desorption ionization time-of-flight/time-of-flight tandem mass spectrometry.	2008	18278818
Synthesis and evaluation of novel biodegradable hydrogels based on poly(ethylene glycol) and sebacic acid as tissue engineering scaffolds.	2008 Jan	18072747
A QSPR for the plasticization efficiency of polyvinylchloride plasticizers.	2008 Jan	17566774
Nanoparticles of polyethylene sebacate: a new biodegradable polymer.	2009	19629708
2-Amino-6-methyl-1,3-benzothia-zole-deca-nedioic acid (2/1).	2009 Aug 19	21577592
Polyethylene sebacate: genotoxicity, mutagenicity evaluation and application in periodontal drug delivery system.	2009 Dec	19455616
Degradation behavior of poly(glycerol sebacate).	2009 Dec 15	19107788
Paraquat induces oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats: neuroprotection and amelioration of symptoms by water-soluble formulation of coenzyme Q10.	2009 Jul 27	19635141
Sampling and analysis of nanoparticles with cold fibre SPME device.	2009 Jun	19425018
Inhaled steroid/tobacco smoke particle interactions: a new light on steroid resistance.	2009 Jun 11	19519905
Medium-chain fatty acids and glutathione derivatives as inhibitors of S-nitrosoglutathione reduction mediated by alcohol dehydrogenase 3.	2009 Jun 15	19428350
Influence of Honey on the Suppression of Human Low Density Lipoprotein (LDL) Peroxidation (In vitro).	2009 Mar	18955249
Six weeks' sebacic acid supplementation improves fasting plasma glucose, HbA1c and glucose tolerance in db/db mice.	2010 Dec	20977585
μ-Decane-dioato-bis-[aqua-bis-(1,10-phenanthroline-κN,N')manganese(II)] dinitrate-sebacic acid-water (1/1/2).	2010 Dec 15	21522598
Glycolic acid modulates the mechanical property and degradation of poly(glycerol, sebacate, glycolic acid).	2010 Jan	19189387
catena-Poly[[[1,2-bis-(benzimidazol-2-yl)ethane]cadmium(II)]-μ-sebacato].	2010 Mar 13	21580506
Effect of oral sebacic Acid on postprandial glycemia, insulinemia, and glucose rate of appearance in type 2 diabetes.	2010 Nov	20724647
Polyethylene sebacate-doxorubicin nanoparticles for hepatic targeting.	2010 Nov 30	20854883

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 20:17:08 GMT 2023` Edited by `admin` on `Sat Dec 16 20:17:08 GMT 2023`
Record UNII	J3YU3MBH4Z
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DISODIUM SEBACATE

Official Name

English

SEBACINE

Brand Name

English

DECANEDIOIC ACID, DISODIUM SALT

Common Name

English

DECANEDIOIC ACID, SODIUM SALT

Common Name

English

DISODIUM DECANEDIOATE

Systematic Name

English

DISODIUM SEBACATE [INCI]

Common Name

English

SEBACIC ACID, DISODIUM SALT

Common Name

English

SA-NA

Common Name

English

Code System Code Type Description

PUBCHEM

134734