Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 13:59:36 GMT 2023
by
admin
on
Sat Dec 16 13:59:36 GMT 2023
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| Protein Type | ENZYME |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
J3XT2E65NQ
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Code System | Code | Type | Description | ||
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Q00987
Created by
admin on Sat Dec 16 13:59:37 GMT 2023 , Edited by admin on Sat Dec 16 13:59:37 GMT 2023
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PRIMARY | |||
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J3XT2E65NQ
Created by
admin on Sat Dec 16 13:59:37 GMT 2023 , Edited by admin on Sat Dec 16 13:59:37 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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INHIBITOR -> TARGET | |||
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LIGAND->TARGET |
Fusion protein that binds HDM2 on cancer cells and leads to lysis of cell. p53-independent HDM2 expression has been reported on the membrane of cancer cells but not on that of normal cells. Herein, we first showed that membrane HDM2 (mHDM2) is exclusively expressed on human and mouse AML blasts, including leukemia stem cell (LSC)-enriched subpopulations, but not on normal hematopoietic stem cells (HSCs).
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Molecular Formula | CHEMICAL |
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| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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