Narlumosbart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 19:31:04 GMT 2023` Edited by `admin` on `Sat Dec 16 19:31:04 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	J38KT46AH8
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Narlumosbart

Official Name

English

gamma4 heavy chain Homo sapiens (1-449) [VH(Homo sapiens IGHV3-23*01 (98.0%)-(IGHD)-IGHJ5*02 (93.8%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122)-Homo sapiens IGHG4*01, G4v5 hP10, nG4m(a) CH2 L92 (CH1(123-220), hinge 1-12, S10>P(230) (221-232), CH2 L

Common Name

English

Immunoglobulin G4 [230-proline], anti-(human osteoclast differentiation factor) (human monoclonal JMT103 γ4-chain), disulfide with human monoclonal JMT103 κ-chain, dimer

Common Name

English

immunoglobulin G4-kappa, anti-[TNFSF11 (tumor necrosis factor (TNF) superfamily member 11, osteoclast differentiation factor, ODF, OPGL, RANKL, TRANCE, CD254)], Homo sapiens monoclonal antibody

Common Name

English

narlumosbart [INN]

Common Name

English

Code System Code Type Description

CAS

2646587-68-8

Created by admin on Sat Dec 16 19:31:04 GMT 2023 , Edited by admin on Sat Dec 16 19:31:04 GMT 2023

PRIMARY

FDA UNII

J38KT46AH8

Created by admin on Sat Dec 16 19:31:04 GMT 2023 , Edited by admin on Sat Dec 16 19:31:04 GMT 2023

PRIMARY

INN

12344

Created by admin on Sat Dec 16 19:31:04 GMT 2023 , Edited by admin on Sat Dec 16 19:31:04 GMT 2023

PRIMARY

NCI_THESAURUS

C190458

Created by admin on Sat Dec 16 19:31:04 GMT 2023 , Edited by admin on Sat Dec 16 19:31:04 GMT 2023

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From	To
1_22	1_96
2_22	2_96
2_136	4_215
2_149	2_205
2_263	2_323
1_136	3_215
2_369	2_427
3_23	3_89
3_135	3_195
4_23	4_89
4_135	4_195
1_149	1_205
1_228	2_228
1_231	2_231
1_263	1_323
1_369	1_427

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					J38KT46AH8

Narlumosbart

ACTIVE MOIETY

Comments:

anti-[TNFSF11 (tumor necrosis factor (TNF) superfamily member 11

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL