HIGH AFFINITY CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 7A

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 02:04:46 GMT 2025` Edited by `admin` on `Wed Apr 02 02:04:46 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	J35DH4R1TA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

HIGH AFFINITY CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 7A

Common Name

English

HCP1

Preferred Name

English

TM22

Common Name

English

PDE7A

Common Name

English

Code System Code Type Description

PHAROS

Q13946

Created by admin on Wed Apr 02 02:04:46 GMT 2025 , Edited by admin on Wed Apr 02 02:04:46 GMT 2025

PRIMARY

UNIPROT

Q13946

Created by admin on Wed Apr 02 02:04:46 GMT 2025 , Edited by admin on Wed Apr 02 02:04:46 GMT 2025

PRIMARY

FDA UNII

J35DH4R1TA

Created by admin on Wed Apr 02 02:04:46 GMT 2025 , Edited by admin on Wed Apr 02 02:04:46 GMT 2025

PRIMARY

Related Record Type Details


					TY56DQ7MZX

MTP-38

INHIBITOR -> TARGET

Comments:

Selective PDE7 inhibitor. Percent inhibition of other PDEs (PDE1A, 3A, 5A, 6, 8A1, 9A2, and 11A4) by 1 ?M of MTP38 were less than 50%.

Qualification:

IC50

Amount:


					263T0E9RR9

DYPHYLLINE

INHIBITOR -> TARGET


					78OY93506O

TOP-1731

INHIBITOR OF EXPRESSION->TARGET

Amount:


					YZC2DS9XDZ

MTP-38 C-11

RADIOLIGAND->TARGET

Comments:

Selective PDE7 inhibitor. Percent inhibition of other PDEs (PDE1A, 3A, 5A, 6, 8A1, 9A2, and 11A4) by 1 ?M of MTP38 were less than 50%.

Qualification:

IC50

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_84]				DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL