U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 22:52:42 UTC 2021
Edited
by admin
on Sat Jun 26 22:52:42 UTC 2021
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
IXO40TAF8X
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TISOTUMAB
INN  
INN   USAN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN BLOOD-COAGULATION FACTOR III) (HUMAN MONOCLONAL HUMAX-TF HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL HUMAX-TF .KAPPA.-CHAIN, DIMER
Systematic Name English
TISOTUMAB [USAN]
Common Name English
TISOTUMAB [INN]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TISSUE FACTOR (COAGULATION FACTOR III, THROMBOPLASTIN, CD142 ANTIGEN, TF))HOMO SAPIENS MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-448) (HOMO SAPIENS VH (IGHV3-23*01 (94%) (IGHD)-IGHJ5*01 (87%)) (8.8.11) (1-118)
Common Name English
HUMAX-TF
Brand Name English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Sat Jun 26 22:52:43 UTC 2021 , Edited by admin on Sat Jun 26 22:52:43 UTC 2021
NCI_THESAURUS C129823
Created by admin on Sat Jun 26 22:52:43 UTC 2021 , Edited by admin on Sat Jun 26 22:52:43 UTC 2021
Code System Code Type Description
INN
10186
Created by admin on Sat Jun 26 22:52:43 UTC 2021 , Edited by admin on Sat Jun 26 22:52:43 UTC 2021
PRIMARY
CAS
1418628-81-5
Created by admin on Sat Jun 26 22:52:43 UTC 2021 , Edited by admin on Sat Jun 26 22:52:43 UTC 2021
PRIMARY
FDA UNII
IXO40TAF8X
Created by admin on Sat Jun 26 22:52:43 UTC 2021 , Edited by admin on Sat Jun 26 22:52:43 UTC 2021
PRIMARY
NCI_THESAURUS
C152664
Created by admin on Sat Jun 26 22:52:43 UTC 2021 , Edited by admin on Sat Jun 26 22:52:43 UTC 2021
PRIMARY
From To
1_22 1_96
1_145 1_201
1_262 1_322
1_368 1_426
2_22 2_96
2_145 2_201
2_262 2_322
2_368 2_426
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_221 3_214
2_221 4_214
1_227 2_227
1_230 2_230
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_298
N 2_298
Related Record Type Details
DERIVATIVE -> PARENT
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL