TISOTUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 22:53:48 GMT 2025` Edited by `admin` on `Mon Mar 31 22:53:48 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	IXO40TAF8X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TISOTUMAB

Official Name

English

tisotumab [INN]

Preferred Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN BLOOD-COAGULATION FACTOR III) (HUMAN MONOCLONAL HUMAX-TF HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL HUMAX-TF .KAPPA.-CHAIN, DIMER

Systematic Name

English

TISOTUMAB [USAN]

Common Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TISSUE FACTOR (COAGULATION FACTOR III, THROMBOPLASTIN, CD142 ANTIGEN, TF))HOMO SAPIENS MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-448) (HOMO SAPIENS VH (IGHV3-23*01 (94%) (IGHD)-IGHJ5*01 (87%)) (8.8.11) (1-118)

Common Name

English

HUMAX-TF

Brand Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN TISSUE FACTOR (ANTIGEN))(HUMAN MONOCLONAL HUMAX-TF HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL HUMAX-TF KAPPA-CHAIN, DIMER

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C20401

Created by admin on Mon Mar 31 22:53:48 GMT 2025 , Edited by admin on Mon Mar 31 22:53:48 GMT 2025

NCI_THESAURUS

C129823

Created by admin on Mon Mar 31 22:53:48 GMT 2025 , Edited by admin on Mon Mar 31 22:53:48 GMT 2025

Code System Code Type Description

RXCUI

2571095

Created by admin on Mon Mar 31 22:53:48 GMT 2025 , Edited by admin on Mon Mar 31 22:53:48 GMT 2025

PRIMARY

INN

10186

Created by admin on Mon Mar 31 22:53:48 GMT 2025 , Edited by admin on Mon Mar 31 22:53:48 GMT 2025

PRIMARY

USAN

GH-176

Created by admin on Mon Mar 31 22:53:48 GMT 2025 , Edited by admin on Mon Mar 31 22:53:48 GMT 2025

PRIMARY

SMS_ID

100000177097

Created by admin on Mon Mar 31 22:53:48 GMT 2025 , Edited by admin on Mon Mar 31 22:53:48 GMT 2025

PRIMARY

CAS

1418628-81-5

Created by admin on Mon Mar 31 22:53:48 GMT 2025 , Edited by admin on Mon Mar 31 22:53:48 GMT 2025

PRIMARY

FDA UNII

IXO40TAF8X

Created by admin on Mon Mar 31 22:53:48 GMT 2025 , Edited by admin on Mon Mar 31 22:53:48 GMT 2025

PRIMARY

NCI_THESAURUS

C152664

Created by admin on Mon Mar 31 22:53:48 GMT 2025 , Edited by admin on Mon Mar 31 22:53:48 GMT 2025

PRIMARY

From	To
1_22	1_96
1_145	1_201
1_262	1_322
1_368	1_426
2_22	2_96
2_145	2_201
2_262	2_322
2_368	2_426
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_221	3_214
2_221	4_214
1_227	2_227
1_230	2_230

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					T41737F88A

TISOTUMAB VEDOTIN

DERIVATIVE -> PARENT

Amount:


					1U5PI2DLU1

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					IXO40TAF8X

TISOTUMAB

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL