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Details

Stereochemistry RACEMIC
Molecular Formula C3H8N2O2.ClH
Molecular Weight 140.569
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,3-DIAMINOPROPIONIC ACID HYDROCHLORIDE

SMILES

Cl.NCC(N)C(O)=O

InChI

InChIKey=SKWCZPYWFRTSDD-UHFFFAOYSA-N
InChI=1S/C3H8N2O2.ClH/c4-1-2(5)3(6)7;/h2H,1,4-5H2,(H,6,7);1H

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C3H8N2O2
Molecular Weight 104.1078
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

PubMed

PubMed

TitleDatePubMed
Highly enantioselective synthesis of alpha,beta-diaminopropanoic acid derivatives using a catalytic asymmetric hydrogenation approach.
2001 Jun 15
Design and synthesis of carboxylate inhibitors for matrix metalloproteinases.
2001 Oct
Gene cloning, purification, and characterization of 2,3-diaminopropionate ammonia-lyase from Escherichia coli.
2002 Dec
Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase.
2002 Nov 12
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum (II) complex linked to the minor groove binder stallimycin.
2003
Radiochemical investigations of gastrin-releasing peptide receptor-specific [(99m)Tc(X)(CO)3-Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH2)] in PC-3, tumor-bearing, rodent models: syntheses, radiolabeling, and in vitro/in vivo studies where Dpr = 2,3-diaminopropionic acid and X = H2O or P(CH2OH)3.
2003 Jul 15
Identification and cloning of genes encoding viomycin biosynthesis from Streptomyces vinaceus and evidence for involvement of a rare oxygenase.
2003 Jul 17
Synthesis of metal-chelating lipids to sensitize lanthanide ions.
2003 May 16
Platinum complexes of diaminocarboxylic acids and their ethyl ester derivatives: the effect of the chelate ring size on antitumor activity and interactions with GMP and DNA.
2003 Sep 1
Synthesis and opioid activity of side-chain-to-side-chain cyclic dynorphin A-(1-11) amide analogues cyclized between positions 2 and 5. 1. Substitutions in position 3.
2004 Jan 15
Synthesis of 9-membered dilactams derived from 1,3-diaminopropionic and glutamic acids.
2004 Mar
Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylglycerol bilayers.
2004 Mar 30
A conventional route for the synthesis of new oxazolidin-2-one derivatives with beta-aminoalanines.
2004 Oct
Inhibition of mitosis by glycopeptide dendrimer conjugates of colchicine.
2005 Jun 20
Synthesis, anti-inflammatory and analgesic activities evaluation of some mono, bi and tricyclic pyrimidine derivatives.
2005 Nov 15
Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.
2005 Sep 5
Electron capture dissociation mass spectrometry of peptide cations containing a lysine homologue: a mobile proton model for explaining the observation of b-type product ions.
2006
Aziridinium from N,N-dibenzyl serine methyl ester: synthesis of enantiomerically pure beta-amino and alpha,beta-diamino esters.
2006 May 11
Structure activity relationship studies on the antimicrobial activity of novel edeine A and D analogues.
2006 Oct
Identification of three Zwittermicin A biosynthesis-related genes from Bacillus thuringiensis subsp. kurstaki strain YBT-1520.
2007 Apr
Identification of a novel beta-replacement reaction in the biosynthesis of 2,3-diaminobutyric acid in peptidylnucleoside mureidomycin A.
2008 Jun 7
A convenient route to enantiopure 3-aryl-2,3-diaminopropanoic acids by diastereoselective Mannich reaction of camphor-based tricyclic iminolactone with imines.
2008 May 2
Beta-N-methylaminoalanine (BMAA): metabolism and metabolic effects in model systems and in neural and other tissues of the rat in vitro.
2009 Aug
Highly enantioselective synthesis of (S)-alpha-alkyl-alpha,beta-diaminopropionic acids via asymmetric phase-transfer catalytic alkylation of 2-phenyl-2-imidazoline-4-carboxylic acid tert-butyl esters.
2009 Aug 20
Identification of catalytic Peptide dendrimers by "off-bead" in silica high-throughput screening of combinatorial libraries.
2009 Jul-Aug
Proteolysis of peptide dendrimers.
2009 Jun 15
N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation.
2009 Mar 15
Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus.
2009 Nov
Structure and binding of peptide-dendrimer ligands to vitamin B12.
2010 Feb 15
Evaluation of [99mTc-(CO)3-X-Y-Bombesin(7-14)NH2] conjugates for targeting gastrin-releasing peptide receptors overexpressed on breast carcinoma.
2010 Jan
Syntheses of bifunctional 2,3-diamino propionic acid-based chelators as small and strong tripod ligands for the labelling of biomolecules with (99m)Tc.
2010 Jun 21
Soluble monometallic salen complexes derived from O-functionalised diamines as metalloligands for the synthesis of heterobimetallic complexes.
2010 May 7
The nonribosomal peptide synthetase enzyme DdaD tethers N(β)-fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-ketoglutarate-dependent epoxidation by DdaC during dapdiamide antibiotic biosynthesis.
2010 Nov 10
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Dec 16 08:20:14 GMT 2023
Edited
by admin
on Sat Dec 16 08:20:14 GMT 2023
Record UNII
IU6ICR549L
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2,3-DIAMINOPROPIONIC ACID HYDROCHLORIDE
MI  
Systematic Name English
2,3-DIAMINOPROPIONIC ACID MONOHYDROCHLORIDE
Systematic Name English
2,3-DIAMINOPROPIONIC ACID HYDROCHLORIDE [MI]
Common Name English
DL-2,3-DIAMINOPROPIONIC ACID HYDROCHLORIDE
Systematic Name English
NSC-90287
Code English
DL-2,3-DIAMINOPROPIONIC ACID MONOHYDROCHLORIDE
Systematic Name English
.ALPHA.,.BETA.-DIAMINOPROPIONIC ACID MONOHYDROCHLORIDE
Systematic Name English
Code System Code Type Description
CAS
54897-59-5
Created by admin on Sat Dec 16 08:20:14 GMT 2023 , Edited by admin on Sat Dec 16 08:20:14 GMT 2023
PRIMARY
NSC
90287
Created by admin on Sat Dec 16 08:20:14 GMT 2023 , Edited by admin on Sat Dec 16 08:20:14 GMT 2023
PRIMARY
PUBCHEM
108638
Created by admin on Sat Dec 16 08:20:14 GMT 2023 , Edited by admin on Sat Dec 16 08:20:14 GMT 2023
PRIMARY
MERCK INDEX
m4256
Created by admin on Sat Dec 16 08:20:14 GMT 2023 , Edited by admin on Sat Dec 16 08:20:14 GMT 2023
PRIMARY Merck Index
FDA UNII
IU6ICR549L
Created by admin on Sat Dec 16 08:20:14 GMT 2023 , Edited by admin on Sat Dec 16 08:20:14 GMT 2023
PRIMARY
EPA CompTox
DTXSID90970223
Created by admin on Sat Dec 16 08:20:14 GMT 2023 , Edited by admin on Sat Dec 16 08:20:14 GMT 2023
PRIMARY