ATAQUIMAST

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H13N3O
Molecular Weight	203.2404
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN1C(=O)C(NC)=NC2=C1C=CC=C2

InChI

InChIKey=ZQAGGAUAOFYNIB-UHFFFAOYSA-N

InChI=1S/C11H13N3O/c1-3-14-9-7-5-4-6-8(9)13-10(12-2)11(14)15/h4-7H,3H2,1-2H3,(H,12,13)

HIDE SMILES / InChI

Molecular Formula	C11H13N3O
Molecular Weight	203.2404
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.jacionline.org/article/S0091-6749(97)81066-4/pdf | https://adisinsight.springer.com/drugs/800010557

Ataquimast, previously known as L0066, inhibits leukotriene release, TNFa and GM-CSF release but have no effect on IL-8 release. This drug participated in clinical trials to treat asthma, but these studies were discontinued.

Originator

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:40:13 GMT 2023` Edited by `admin` on `Fri Dec 15 15:40:13 GMT 2023`
Record UNII	II3F5A2G0F
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ATAQUIMAST

Official Name

English

1-ETHYL-3-(METHYLAMINO)-2(1H)-QUINOXALINONE

Systematic Name

English

ataquimast [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29712