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Details

Stereochemistry ACHIRAL
Molecular Formula Mn.O4S
Molecular Weight 151.001
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MANGANOUS SULFATE ANHYDROUS

SMILES

[Mn++].[O-]S([O-])(=O)=O

InChI

InChIKey=SQQMAOCOWKFBNP-UHFFFAOYSA-L
InChI=1S/Mn.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2

HIDE SMILES / InChI

Molecular Formula O4S
Molecular Weight 96.063
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Mn
Molecular Weight 54.938
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Manganese citrate is generally recognized as safe direct food additive. Manganese citrate complex has being used in the determination of liver enzyme activities in the aging process and following treatment with aminoethylisothiuronium bromide hydrobromide (AET).

Approval Year

Targets

Targets

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Manganese is used for prevention and treatment of manganese deficiency, a condition in which the body doesn’t have enough manganese.
Primary
Unknown

Approved Use

Manganese is used for weak bones (osteoporosis).
Palliative
Unknown

Approved Use

Early research suggests that taking manganese along with calcium helps improve symptoms of PMS, including pain, crying, loneliness, anxiety, restlessness, irritability, mood swings, depression, and tension.
Curative
MANGANESE SULFATE

Approved Use

Manganese Sulfate Injection, USP is indicated for use as a supplement to intravenous solutions given for Total Parenteral Nutrition (TPN). Administration helps to maintain plasma levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.
Primary
MANGANESE SULFATE

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Cytochrome oxidase determination using a manganese citrate complex.
1970
Metabolism of l-Tyrosine to 4-Hydroxybenzaldehyde and 3-Bromo-4-Hydroxybenzaldehyde by Chloroplast-containing Fractions of Odonthalia floccosa (Esp.) Falk.
1979 Dec
Effect of fluoride on copper, manganese and zinc in bone and kidney.
1981 Mar
Effect of quantity and route of administration of manganese monoxide on feed intake and serum manganese in ruminants.
1985 Feb
Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure.
1993 Jul
Dietary calcium and manganese effects on menstrual cycle symptoms.
1993 May
Manganese citrate improves base-calling accuracy in DNA sequencing reactions using rhodamine-based fluorescent dye-terminators.
1999 Mar 1
Manganese citrate chemistry: syntheses, spectroscopic studies, and structural characterizations of novel mononuclear, water-soluble manganese citrate complexes.
2000 Sep 4
Differential ability of transition metals to induce pulmonary inflammation.
2001 Nov 15
Tetraaqua(1,10-phenanthroline-kappa(2)N,N')manganese(II) sulfate dihydrate.
2002 Jul
Is the axial zero-field splitting parameter of tetragonally elongated high-spin manganese(III) complexes always negative?
2002 Jul 31
Glutamate/aspartate transporter (GLAST), taurine transporter and metallothionein mRNA levels are differentially altered in astrocytes exposed to manganese chloride, manganese phosphate or manganese sulfate.
2002 Sep
Bi- and poly-metallic cyanide-bridged complexes of the redox-active cyanomanganese nitrosyl unit [Mn(CN)(PR3)(NO)(eta-C5H4Me)].
2004 Feb 21
Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity.
2007 Jun
Effects of chronic manganese exposure on glutamatergic and GABAergic neurotransmitter markers in the nonhuman primate brain.
2009 Sep
Expression profile analysis of antioxidative stress and developmental pathway genes in the manganese-exposed intertidal copepod Tigriopus japonicus with 6K oligochip.
2013 Aug
Controlled Synthesis of Hollow Manganese Oxide Nanocrystals.
2016 Feb
Chronic exposure to manganese sulfate leads to adverse dose-dependent effects on the neurobehavioral ability of rats.
2016 Nov
Yolk-Shell MnO@ZnMn(2) O(4) /N-C Nanorods Derived from α-MnO(2) /ZIF-8 as Anode Materials for Lithium Ion Batteries.
2016 Oct
Top-Down Strategy to Synthesize Mesoporous Dual Carbon Armored MnO Nanoparticles for Lithium-Ion Battery Anodes.
2017 Apr 12
Intramolecular Aminoalkoxylation of Unfunctionalized Olefins via Intramolecular Iodoamination and Aziridinium Ion Ring-Opening Sequence.
2017 Apr 7
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Curator's Comment: In vitro cytotoxicity of manganese oxide (MnO) using live/dead cell assay, lactate dehydrogenase assay, and reactive oxygen species detection with variation of the concentration of nanoparticles (5-500 ug/ml), incubation time (18-96 h), and different human cell lines (lung adenocarcinoma, breast cancer cells, and glioblastoma cells) was studied. The cytotoxic effect was negligible for 18 h incubation even at highest concentration of 500 ug/ml MnO nanoparticle.
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:57:44 UTC 2023
Edited
by admin
on Fri Dec 15 15:57:44 UTC 2023
Record UNII
IGA15S9H40
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MANGANOUS SULFATE ANHYDROUS
Common Name English
MANGANESE (AS SULFATE) [VANDF]
Common Name English
MANGANESE(2+) SULPHATE (1:1)
Systematic Name English
MANGANESE SULPHATE ANHYDROUS
Common Name English
MANGANESE SULFATE, ANHYDROUS
Common Name English
Manganese sulfate [WHO-DD]
Common Name English
MANGANESE(2+) SULFATE (1:1)
Systematic Name English
MANGANESE SULFATE ANHYDROUS [HSDB]
Common Name English
MANGANESE SULFATE (ANHYDROUS)
Common Name English
MANGANI(II) SULFAS ANHYDRICUS
Common Name English
MANGANESE SULFATE [MI]
Common Name English
Sulfuric acid, manganese(2+) salt (1:1)
Systematic Name English
MANGANESE SULFATE ANHYDROUS
HSDB  
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29730
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
Code System Code Type Description
PUBCHEM
24580
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
NCI_THESAURUS
C76658
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
WIKIPEDIA
Manganese(II) sulfate
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
MERCK INDEX
m7074
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY Merck Index
EPA CompTox
DTXSID9044160
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
CHEBI
86360
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
CAS
7785-87-7
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
FDA UNII
IGA15S9H40
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
SMS_ID
100000076490
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
HSDB
2187
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
ECHA (EC/EINECS)
232-089-9
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
RXCUI
1746493
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
DAILYMED
IGA15S9H40
Created by admin on Fri Dec 15 15:57:44 UTC 2023 , Edited by admin on Fri Dec 15 15:57:44 UTC 2023
PRIMARY
Related Record Type Details
SOLVATE->ANHYDROUS
PARENT -> SALT/SOLVATE
SOLVATE->ANHYDROUS
Related Record Type Details
ACTIVE MOIETY