APATORSEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 17:37:19 UTC 2023` Edited by `admin` on `Sat Dec 16 17:37:19 UTC 2023`
Nucleic Acid Type	OLIGONUCLEOTIDE
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	IFJ6X26JW6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

APATORSEN

Official Name

English

Apatorsen [WHO-DD]

Common Name

English

APATORSEN [USAN]

Common Name

English

apatorsen [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1291

Created by admin on Sat Dec 16 17:37:19 UTC 2023 , Edited by admin on Sat Dec 16 17:37:19 UTC 2023

Code System Code Type Description

INN

9858

Created by admin on Sat Dec 16 17:37:19 UTC 2023 , Edited by admin on Sat Dec 16 17:37:19 UTC 2023

PRIMARY

ChEMBL

CHEMBL3039556

Created by admin on Sat Dec 16 17:37:19 UTC 2023 , Edited by admin on Sat Dec 16 17:37:19 UTC 2023

PRIMARY

PUBCHEM

71710946

Created by admin on Sat Dec 16 17:37:19 UTC 2023 , Edited by admin on Sat Dec 16 17:37:19 UTC 2023

PRIMARY

EPA CompTox

DTXSID20143044

Created by admin on Sat Dec 16 17:37:19 UTC 2023 , Edited by admin on Sat Dec 16 17:37:19 UTC 2023

PRIMARY

USAN

AB-38

Created by admin on Sat Dec 16 17:37:19 UTC 2023 , Edited by admin on Sat Dec 16 17:37:19 UTC 2023

PRIMARY

FDA UNII

IFJ6X26JW6

Created by admin on Sat Dec 16 17:37:19 UTC 2023 , Edited by admin on Sat Dec 16 17:37:19 UTC 2023

PRIMARY

CAS

1002331-21-6

Created by admin on Sat Dec 16 17:37:19 UTC 2023 , Edited by admin on Sat Dec 16 17:37:19 UTC 2023

PRIMARY

NCI_THESAURUS

C71740

Created by admin on Sat Dec 16 17:37:19 UTC 2023 , Edited by admin on Sat Dec 16 17:37:19 UTC 2023

PRIMARY

DRUG BANK

DB06094

Created by admin on Sat Dec 16 17:37:19 UTC 2023 , Edited by admin on Sat Dec 16 17:37:19 UTC 2023

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methyl-Ribose	1_1-1_4;1_17-1_20	8 / 20
Deoxyribose (DNA)	1_5-1_16	12 / 20

Linkage	Site Range	Site Count
Phosporothioate	1_2-1_20	19 / 19

Related Record Type Details


					IFJ6X26JW6

APATORSEN

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOSIDE_SUBSTITUTION	[1_5] [1_7] [1_10] [1_12] [1_14]	SITE_SPECIFIC			5-METHYLDEOXYCYTIDINE	B200GV71QM
NUCLEOSIDE_SUBSTITUTION	[1_17] [1_20]	SITE_SPECIFIC			2'-O-(2-METHOXYETHYL)-5-METHYLURIDINE	9Q36I4D9VB