Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Tue Apr 01 17:04:21 GMT 2025
by
admin
on
Tue Apr 01 17:04:21 GMT 2025
|
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
ICW5U9V0SL
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Preferred Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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P53778
Created by
admin on Tue Apr 01 17:04:21 GMT 2025 , Edited by admin on Tue Apr 01 17:04:21 GMT 2025
|
PRIMARY | |||
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ICW5U9V0SL
Created by
admin on Tue Apr 01 17:04:21 GMT 2025 , Edited by admin on Tue Apr 01 17:04:21 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
WEAK INHIBITOR->TARGET |
Enzyme inhibition
IC50
|
![Structure of N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N?-[4-[[2-(phenylamino)-4-pyrimidinyl]oxy]-1-naphthalenyl]urea](/img/aba6147e-73c3-4a00-bb0c-3de192f48ea3.svg "Structure of N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N?-[4-[[2-(phenylamino)-4-pyrimidinyl]oxy]-1-naphthalenyl]urea")
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| AMINO ACID SUBSTITUTION | [1_185] | TYROSINE O-PHOSPHATE | 2R86C98KDX | |||
| AMINO ACID SUBSTITUTION | [1_183] | THREONINE PHOSPHATE | 3L4WX7B1EI |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
|
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| Molecular Formula | CHEMICAL |
|