Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C17H25N3O2S |
| Molecular Weight | 335.464 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)C1=C2C=CC=C(C2=CC=C1)S(=O)(=O)NCCCCCN
InChI
InChIKey=MLEBFEHOJICQQS-UHFFFAOYSA-N
InChI=1S/C17H25N3O2S/c1-20(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)19-13-5-3-4-12-18/h6-11,19H,3-5,12-13,18H2,1-2H3
| Molecular Formula | C17H25N3O2S |
| Molecular Weight | 335.464 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| IGF-1 induces expression of zinc-finger protein 143 in colon cancer cells through phosphatidylinositide 3-kinase and reactive oxygen species. | 2010-10-31 |
|
| Caveolae-mediated entry of Salmonella typhimurium into senescent nonphagocytotic host cells. | 2010-04 |
|
| A novel array-based assay of in situ tissue transglutaminase activity in human umbilical vein endothelial cells. | 2009-11-15 |
|
| Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation. | 2009-10 |
|
| Alternative infectious entry pathways for dengue virus serotypes into mammalian cells. | 2009-10 |
|
| Molecular MRI of early thrombus formation using a bimodal alpha2-antiplasmin-based contrast agent. | 2009-08 |
|
| Possible role for cellular FXIII in monocyte-derived dendritic cell motility. | 2009-08 |
|
| New insights into the expression and role of platelet factor XIII-A. | 2009-07 |
|
| Phenotype-dependent apoptosis signalling in mesothelioma cells after selenite exposure. | 2009-06-29 |
|
| RhoA and Rho kinase activation in human pulmonary hypertension: role of 5-HT signaling. | 2009-06-15 |
|
| Serotonylation of vascular proteins important to contraction. | 2009-05-25 |
|
| Route to smooth silica-based surfaces decorated with novel self-assembled monolayers (SAMs) containing glycidyl-terminated very long hydrocarbon chains. | 2009-05-19 |
|
| Biochemical characterization of bovine plasma thrombin-activatable fibrinolysis inhibitor (TAFI). | 2009-05-05 |
|
| Naphthoimidazoles promote different death phenotypes in Trypanosoma cruzi. | 2009-04 |
|
| The human complement fragment receptor, C5L2, is a recycling decoy receptor. | 2009-03 |
|
| Internalization of the receptor for advanced glycation end products (RAGE) is required to mediate intracellular responses. | 2009-01 |
|
| SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway. | 2008-12 |
|
| Effect of acetylcholine precursors on proliferation and differentiation of astroglial cells in primary cultures. | 2008-12 |
|
| Effect of choline-containing phospholipids on transglutaminase activity in primary astroglial cell cultures. | 2008-11 |
|
| Autophagic and apoptotic cell death in amniotic epithelial cells. | 2008-11 |
|
| RNAi screen of endoplasmic reticulum-associated host factors reveals a role for IRE1alpha in supporting Brucella replication. | 2008-07-25 |
|
| Vasoconstrictor effect of aldosterone via angiotensin II type 1 (AT1) receptor: possible role of AT1 receptor dimerization. | 2008-07-01 |
|
| Mechanisms of adrenocorticotropin-induced activation of extracellularly regulated kinase 1/2 mitogen-activated protein kinase in the human H295R adrenal cell line. | 2008-04 |
|
| Extracellular transglutaminase 2 is catalytically inactive, but is transiently activated upon tissue injury. | 2008-03-26 |
|
| An excellent monitoring system for surface ubiquitination-induced internalization in mammals. | 2008-01-30 |
|
| Characterizing the anti-HIV activity of papuamide A. | 2008 |
|
| Magnolol-induced H460 cells death via autophagy but not apoptosis. | 2007-12 |
|
| Signaling induced by hop/STI-1 depends on endocytosis. | 2007-06-29 |
|
| Autophagy is involved in cytotoxic effects of crotoxin in human breast cancer cell line MCF-7 cells. | 2007-04 |
|
| Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells. | 2007-02-02 |
|
| Inhibition of receptor internalization attenuates the TNFalpha-induced ROS generation in non-phagocytic cells. | 2006-12-29 |
|
| Transglutaminase participates in UVB-induced cell death pathways in human corneal epithelial cells. | 2006-10 |
|
| Tissue-transglutaminase contributes to neutrophil granulocyte differentiation and functions. | 2006-09-15 |
|
| Programmed cell death of the ovarian nurse cells during oogenesis of the silkmoth Bombyx mori. | 2006-09 |
|
| Biochemical characterization and cloning of transglutaminases responsible for hemolymph clotting in Penaeus monodon and Marsupenaeus japonicus. | 2006-07 |
|
| Expression and regulation of cornified envelope proteins in human corneal epithelium. | 2006-05 |
|
| Proteasomal proteolysis in anoxia-reoxygenation, preconditioning and postconditioning of isolated cardiomyocytes. | 2006-05 |
|
| Cytosolic entry of bisphosphonate drugs requires acidification of vesicles after fluid-phase endocytosis. | 2006-05 |
|
| Cross linking to tissue transglutaminase and collagen favours gliadin toxicity in coeliac disease. | 2006-04 |
|
| Factor XIIIa mediated attachment of S. aureus fibronectin-binding protein A (FnbA) to fibrin: identification of Gln103 as a major cross-linking site. | 2006-02-14 |
|
| Endocytosis of beta1 integrins is an early event in migration promoted by the cell adhesion molecule L1. | 2006-02-01 |
|
| Effects of tissue transglutaminase on beta -amyloid1-42-induced apoptosis. | 2006-01 |
|
| Tissue transglutaminase serves as an inhibitor of apoptosis by cross-linking caspase 3 in thapsigargin-treated cells. | 2006-01 |
|
| Proteasome inhibitors eliminate protective effect of postconditioning in cultured neonatal cardiomyocytes. | 2006 |
|
| Purification and partial characterization of the plasma clotting protein from the pink shrimp Farfantepenaeus paulensis. | 2005-11 |
|
| Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas. | 2005-09 |
|
| Macrophages rapidly transfer pathogens from lipid raft vacuoles to autophagosomes. | 2005-04 |
|
| Postconditioning prevents apoptotic necrotic and autophagic cardiomyocyte cell death in culture. | 2005 |
|
| More than one type of transglutaminase in invertebrates? A second type of transglutaminase is involved in shrimp coagulation. | 2005 |
|
| Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds. | 1997-12-24 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:37:56 GMT 2025
by
admin
on
Mon Mar 31 19:37:56 GMT 2025
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| Record UNII |
I9N81SC5HD
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID40143788
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4247
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I9N81SC5HD
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233-326-9
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52007
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