2,6-Xylenol

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H10O
Molecular Weight	122.1644
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC=CC(C)=C1O

InChI

InChIKey=NXXYKOUNUYWIHA-UHFFFAOYSA-N

InChI=1S/C8H10O/c1-6-4-3-5-7(2)8(6)9/h3-5,9H,1-2H3

HIDE SMILES / InChI

Molecular Formula	C8H10O
Molecular Weight	122.1644
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
9-(2,6-Dimethyl-phen-oxy-carbon-yl)-10-methyl-acridinium trifluoro-methane-sulfonate.	2010-10-23	21589102
Gas-phase phenol methylation over Mg/Me/O (Me = Al, Cr, Fe) catalysts: mechanistic implications due to different acid-base and dehydrogenating properties.	2010-09-28	20689870
Controlled synthesis of mononuclear or binuclear aryloxo ytterbium complexes supported by beta-diketiminate ligand and their activity for polymerization of epsilon-caprolactone and L-lactide.	2010-08-07	20571684
Chemical oxidation of 2,6-dimethylaniline by electrochemically generated Fenton's reagent.	2010-04-15	19963316
Catalytic carbon-carbon bond-forming reactions of aminoalkane derivatives with imines.	2010-03-17	20166665
Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy)acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: a prodrug strategy for targeting cytoprotective antioxidants to mitochondria.	2010-02-15	20129794
Kinetics and mechanism of 2,6-dimethyl-aniline degradation by hydroxyl radicals.	2009-12-30	19692169
Chemical oxidation of 2,6-dimethylaniline in the fenton process.	2009-11-15	20028063
Coupling poly-(methacrylic acid-co-ethylene glycol dimethacrylate) monolith microextraction to capillary electrophoresis for the determination of phenols in water samples.	2009-06-15	19362223
Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064.	2009-06-01	19410460
Reaction of an oxaruthenacycle with DMAD. Stoichiometric transformations of 2,6-xylenol to allylic phenols and benzopyrans via sp(3) C-H bond cleavage reaction.	2009-05-07	19421629
Novel multiwalled carbon nanotubes-polyaniline composite film coated platinum wire for headspace solid-phase microextraction and gas chromatographic determination of phenolic compounds.	2009-05-01	19306999
Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols.	2009-04-15	19231207
Potential of Penicillium species in the bioremediation field.	2009-04	19440525
Two methods for catalytic generation of reactive enolates promoted by a chiral poly gd complex: application to catalytic enantioselective protonation reactions.	2009-03-25	19249830
Proton-coupled electron-transfer oxidation of phenols by hexachloroiridate(IV).	2008-12-15	19006385
Engineering and Applications of fungal laccases for organic synthesis.	2008-11-20	19019256
trans-4-[(2,6-Dimethyl-phen-oxy)methyl]cyclo-hexa-necarboxylic acid.	2008-11-08	21581244
Selective and stability-indicating methods for the simultaneous determination of mexiletine hydrochloride and/or its related substance: 2,6-dimethylphenol.	2008-08-30	18727529
[New promising antioxidants based on 2,6-dimethylphenol].	2008-08-13	18695730
Synthesis of (1-adamantylimido)vanadium(V) complexes containing aryloxo, ketimide ligands: effect of ligand substituents in olefin insertion/metathesis polymerization.	2008-07-21	18557610
Versatile scorpionates and new developments in the denticity changes of NNCp hybrid scorpionate/cyclopentadienyl ligands in Sc and Y compounds: from kappa1-Neta5-Cp to kappa2-NNeta5-Cp.	2008-06-02	18447332
[New efficient producers of fungal laccases].	2008-05-22	18491602
A catalytic enantioselective conjugate addition of cyanide to enones.	2008-05-14	18419119
Synthesis, magnetic behaviour, and X-ray structures of dinuclear copper complexes with multiple bridges. Efficient and selective catalysts for polymerization of 2,6-dimethylphenol.	2007-06-21	17844662
Detailed examination of the degradation of phenol derivatives under oxygen delignification conditions.	2007-02-21	17300151
Determination of chlorine dioxide in water by gas chromatography-mass spectrometry.	2006-08-04	16716337
Tropospheric multiphase chemistry of 2,5- and 2,6-dimethylphenols: determination of the mass accommodation coefficients and the Henry's law constants.	2006-04-14	16633656
High-affinity blockade of voltage-operated skeletal muscle sodium channels by 2,6-dimethyl-4-chlorophenol.	2006-03	16430789
[Inhibitory effects of phenolic ecotoxicants on photobacteria at various pH values].	2005-12-20	16358753
Selective oxidative para C-C dimerization of 2,6-dimethylphenol.	2005-12-14	16307153
A comparative study of water soluble 5,10,15,20-tetrakis(2,6-dichloro-3-sulfophenyl)porphyrin and its metal complexes as efficient sensitizers for photodegradation of phenols.	2005-08	16052268
Structural features of phenol derivatives determining potency for activation of chloride currents via alpha(1) homomeric and alpha(1)beta heteromeric glycine receptors.	2005-08	15912136
Antioxidant activity of propofol and related monomeric and dimeric compounds.	2005-03	15744114
Effects of speciation on partitioning of iodine in aqueous biphasic systems and onto ABEC resins.	2004-07-25	15177173
Polymer-based adsorption medium prepared using a fragment imprinting technique for homologues of chlorinated bisphenol A produced in the environment.	2004-03-12	15032347
Evaluation of the antioxidant properties of propofol and its nitrosoderivative. comparison with homologue substituted phenols.	2004-03	15129739
Luminescence quenching of tris(2,2'-bipyridine)ruthenium(II) by 2,6-dimethylphenol and 4-bromo-2,6-dimethylphenol in sol-gel-processed silicate thin films.	2004-02-15	14697702
Oxidative polymerization of 2,6-dimethylphenol to form poly(2,6-dimethyl-1,4-phenyleneoxide) in water.	2004-01-30	14755705
An improved model for the binding of lidocaine and structurally related local anaesthetics to fast-inactivated voltage-operated sodium channels, showing evidence of cooperativity.	2004-01	14662728
Phenol and lactone receptors in the distal sensilla of the Haller's organ in Ixodes ricinus ticks and their possible role in host perception.	2004	15139275
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na(+) channels.	2003-11-20	14613326
Depolymerization of poly(2,6-dimethyl-1,4-phenylene oxide) under oxidative conditions.	2003-09-05	12953209
Molybdenum-phosphorus triple bond stabilization by ancillary alkoxide ligation: synthesis and structure of a terminal phosphide tris-1-methylcyclohexanoxide complex.	2003-08-06	12889934
Glucuronidation of propofol and its analogs by human and rat liver microsomes.	2003-02	12576683
Vibrational analysis of substituted phenols: part II. Transferability of valence force constants.	2002-12	12511105
Block of voltage-operated sodium channels by 2,6-dimethylphenol, a structural analogue of lidocaine's aromatic tail.	2002-09	12208786
Chiral proton donor reagents: tin tetrachloride--coordinated optically active binaphthol derivatives.	2002	12112869
Structural requirements of phenol derivatives for direct activation of chloride currents via GABA(A) receptors.	2001-06-08	11399263
Estimation of glycated hemoglobin by 2,6-dimethylphenol: Sulphuric acid conventional method.	2001-01	23105290

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:39:36 GMT 2025` Edited by `admin` on `Mon Mar 31 19:39:36 GMT 2025`
Record UNII	I8N0RO87OV
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2,6-Xylenol

Systematic Name

English

2,6-DIMETHYLPHENOL

Preferred Name

English

DIMETHYLPHENOL, 2,6-

Systematic Name

English

XYLENOL 2,6-DIMETHYLPHENOL [MI]

Common Name

English

XYLENOL 2,6-DIMETHYLPHENOL

Systematic Name

English

2,6-XYLENOL [FHFI]

Common Name

English

NSC-2123

Code

English

2,6-DIMETHYLPHENOL [HSDB]

Common Name

English

FEMA NO. 3249

Code

English

1-HYDROXY-2,6-DIMETHYLBENZENE

Systematic Name

English

MEXILETINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]

Common Name

English

METACRESOL IMPURITY D [EP IMPURITY]

Common Name

English

Classification Tree Code System Code

JECFA EVALUATION

2,6-XYLENOL