U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C7H14O8.Tc
Molecular Weight 325.0875
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TECHNETIUM TC-99M GLUCEPTATE

SMILES

[99Tc].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)C(O)=O

InChI

InChIKey=FWONYTNJVVDALD-NEXMAILDSA-N
InChI=1S/C7H14O8.Tc/c8-1-2(9)3(10)4(11)5(12)6(13)7(14)15;/h2-6,8-13H,1H2,(H,14,15);/t2-,3-,4+,5-,6-;/m1./s1/i;1+1

HIDE SMILES / InChI
Molecular Formula Tc
Molecular Weight 98.9063
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C7H14O8
Molecular Weight 226.1813
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

1973
98
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Approved
8429
OSTEOLITE

Approved Use

Unknown

Launch Date

1977
Diagnostic
Approved
8429
DRAXIMAGE MDP-10

Approved Use

MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis.

Launch Date

1978
PubMed

PubMed

TitleDatePubMed
Future of low specific activity molybdenum-99/technetium-99m generator.
2012 Oct
Patents

Patents

20050082469
43

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:57:26 GMT 2023
Edited
by admin
on Fri Dec 15 15:57:26 GMT 2023
Record UNII
I853LE095B
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
TECHNETIUM TC-99M GLUCEPTATE
Common Name English
TECHNETIUM TC 99M GLUCEPTATE [USP IMPURITY]
Common Name English
Technetium tc 99m gluceptate [WHO-DD]
Common Name English
GLUCOHEPTONIC ACID COMPLEX WITH 99MTC [MI]
Common Name English
GLUCOHEPTONIC ACID COMPLEX WITH 99MTC
MI  
Common Name English
TECHNETIUM TC 99M GLUCEPTATE
USP   WHO-DD  
Common Name English
TECHNETIUM 99MTC GLUCOHEPTONATE
Common Name English
Classification Tree Code System Code
NDF-RT N0000177914
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
WHO-ATC V09CA04
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
NDF-RT N0000000205
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
NCI_THESAURUS C2124
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
WHO-VATC QV09CA04
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
Code System Code Type Description
SMS_ID
100000092201
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
PRIMARY
FDA UNII
I853LE095B
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
PRIMARY
LACTMED
Technetium 99mTc Glucoheptonate
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110570
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
PRIMARY
NCI_THESAURUS
C87403
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
PRIMARY
MERCK INDEX
m5761
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
PRIMARY Merck Index
PUBCHEM
49800005
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
PRIMARY
MESH
C100014
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
PRIMARY
EVMPD
SUB15469MIG
Created by admin on Fri Dec 15 15:57:26 GMT 2023 , Edited by admin on Fri Dec 15 15:57:26 GMT 2023
PRIMARY
Related Record Type Details
Structure of GLUCOHEPTONIC ACID
PARENT -> SALT/SOLVATE
TECHNETIUM TC-99M GLUCEPTATE KIT
SUB_CONCEPT->SUBSTANCE
Structure of TECHNETIUM TC-99M
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of TECHNETIUM TC-99M
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966