Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C10H18N2O3 |
| Molecular Weight | 214.2615 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@@H]1NC(=O)N[C@@H]1CCCCCC(O)=O
InChI
InChIKey=AUTOLBMXDDTRRT-JGVFFNPUSA-N
InChI=1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1
| Molecular Formula | C10H18N2O3 |
| Molecular Weight | 214.2615 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Interaction-dependent PCR: identification of ligand-target pairs from libraries of ligands and libraries of targets in a single solution-phase experiment. | 2010-11-10 |
|
| Overexpression of biotin synthase and biotin ligase is required for efficient generation of sulfur-35 labeled biotin in E. coli. | 2010-10-11 |
|
| Protein trans-splicing on an M13 bacteriophage: towards directed evolution of a semisynthetic split intein by phage display. | 2010-10 |
|
| A selective assay to detect chitin and biologically active nano-machineries for chitin-biosynthesis with their intrinsic chitin-synthase molecules. | 2010-09-07 |
|
| Blood-to-retina transport of biotin via Na+-dependent multivitamin transporter (SMVT) at the inner blood-retinal barrier. | 2010-09 |
|
| The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. | 2010-08-25 |
|
| Selenocysteine, pyrrolysine, and the unique energy metabolism of methanogenic archaea. | 2010-08-17 |
|
| Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . | 2010-08-10 |
|
| Superpose3D: a local structural comparison program that allows for user-defined structure representations. | 2010-08-05 |
|
| Affinity recovery of lentivirus by diaminopelargonic acid mediated desthiobiotin labelling. | 2010-07-15 |
|
| Phosphorylation and methylation of proteasomal proteins of the haloarcheon Haloferax volcanii. | 2010-07-08 |
|
| Synthesis of 5-hydroxyectoine from ectoine: crystal structure of the non-heme iron(II) and 2-oxoglutarate-dependent dioxygenase EctD. | 2010-05-14 |
|
| Time-resolved structural studies of protein reaction dynamics: a smorgasbord of X-ray approaches. | 2010-03 |
|
| A combined computational and experimental investigation of the [2Fe-2S] cluster in biotin synthase. | 2010-02 |
|
| Lactococcus lactis, an alternative system for functional expression of peripheral and intrinsic Arabidopsis membrane proteins. | 2010-01-20 |
|
| Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] . | 2010-01-06 |
|
| Sequestosome-1/p62 is the key intracellular target of innate defense regulator peptide. | 2009-12-25 |
|
| A complex between biotin synthase and the iron-sulfur cluster assembly chaperone HscA that enhances in vivo cluster assembly. | 2009-11-17 |
|
| The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels. | 2009-11-03 |
|
| Versatile dual reporter gene systems for investigating stop codon readthrough in plants. | 2009-10-09 |
|
| Adjustable ellipsoid nanoparticles assembled from re-engineered connectors of the bacteriophage phi29 DNA packaging motor. | 2009-08-25 |
|
| The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains. | 2009-07-14 |
|
| Differences between CusA and AcrB crystallisation highlighted by protein flexibility. | 2009-07-10 |
|
| Protein residues that control the reaction trajectory in S-adenosylmethionine radical enzymes: mutagenesis of asparagine 153 and aspartate 155 in Escherichia coli biotin synthase. | 2009-03-24 |
|
| Structural insight into nucleotide recognition by human death-associated protein kinase. | 2009-03 |
|
| Vitreal pharmacokinetics of biotinylated ganciclovir: role of sodium-dependent multivitamin transporter expressed on retina. | 2009-02 |
|
| Fabrication of massive sheets of single layer patterned arrays using lipid directed reengineered phi29 motor dodecamer. | 2009-01-27 |
|
| A novel Ecotin-Ubiquitin-Tag (ECUT) for efficient, soluble peptide production in the periplasm of Escherichia coli. | 2009-01-21 |
|
| Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue. | 2009-01-07 |
|
| Selection of smart small-molecule ligands: the proof of principle. | 2009-01-01 |
|
| Poisoning pyridoxal 5-phosphate-dependent enzymes: a new strategy to target the malaria parasite Plasmodium falciparum. | 2009 |
|
| Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily. | 2009 |
|
| Repetitive architecture of the Haemophilus influenzae Hia trimeric autotransporter. | 2008-12-26 |
|
| Growth of Yersinia pseudotuberculosis in human plasma: impacts on virulence and metabolic gene expression. | 2008-12-03 |
|
| Directed evolution of streptavidin variants using in vitro compartmentalization. | 2008-09-22 |
|
| 9-Mercaptodethiobiotin is formed as a competent catalytic intermediate by Escherichia coli biotin synthase. | 2008-09-02 |
|
| Ligand specificity of group I biotin protein ligase of Mycobacterium tuberculosis. | 2008-05-28 |
|
| Importance of the maintenance pathway in the regulation of the activity of Escherichia coli ribonucleotide reductase. | 2008-04-01 |
|
| Stochastic resonance reveals "pilot light" expression in mammalian genes. | 2008-03-26 |
|
| The assembly of the plasmodial PLP synthase complex follows a defined course. | 2008-03-19 |
|
| Loss of iron-sulfur clusters from biotin synthase as a result of catalysis promotes unfolding and degradation. | 2008-03-01 |
|
| Fluorescence labeling of a cytokine with desthiobiotin-tagged fluorescent puromycin. | 2008-03 |
|
| Purification of His-tagged proteins with [desthiobiotin-BSA-EDTA] conjugates exhibiting resistance to EDTA. | 2008-03 |
|
| A bifunctional locus (BIO3-BIO1) required for biotin biosynthesis in Arabidopsis. | 2008-01 |
|
| Quorum sensing primes the oxidative stress response in the insect endosymbiont, Sodalis glossinidius. | 2008 |
|
| A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes. | 2007-12 |
|
| In vivo resolution of conflicting in vitro results: synthesis of biotin from dethiobiotin does not require pyridoxal phosphate. | 2007-11 |
|
| Method for screening and MALDI-TOF MS sequencing of encoded combinatorial libraries. | 2007-10-01 |
|
| Quantitative multiplex detection of plant pathogens using a novel ligation probe-based system coupled with universal, high-throughput real-time PCR on OpenArrays. | 2007-08-14 |
|
| New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor, revealed by combined proteomic and transcriptomic analysis of liquid cultures. | 2007-08-02 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:11:09 GMT 2025
by
admin
on
Mon Mar 31 22:11:09 GMT 2025
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| Record UNII |
I64P0B487B
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| Record Status |
Validated (UNII)
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| Record Version |
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203773
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15720-25-9
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I64P0B487B
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3085
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636-20-4
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