BUTIKACIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H45N5O12
Molecular Weight	571.619
Optical Activity	UNSPECIFIED
Defined Stereocenters	16 / 16
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]3(O[C@H]1[C@@H](C[C@H](N)[C@@H](O[C@@]2([H])O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]1O)NC[C@@H](O)CCN)O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O

InChI

InChIKey=OCFOTEIMZBKQFS-DGMGPCKZSA-N

InChI=1S/C22H45N5O12/c23-2-1-7(29)5-27-9-3-8(25)19(38-22-17(34)16(33)14(31)10(4-24)36-22)18(35)20(9)39-21-15(32)12(26)13(30)11(6-28)37-21/h7-22,27-35H,1-6,23-26H2/t7-,8-,9+,10+,11+,12-,13+,14+,15+,16-,17+,18-,19+,20-,21+,22+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C22H45N5O12
Molecular Weight	571.619
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	16 / 16
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/591447 | https://www.ncbi.nlm.nih.gov/pubmed/100050 | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19760506&CC=DE&NR=2547738A1&KC=A1

Butikacin is deoxystreptamine aminoglycoside with bactericidal activity with good activity against Staphylococcus aureus and a range of gram-negative bacteria.

Originator

Approval Year

PubMed

Title	Date	PubMed
Synthesis and antibacterial activities of 1-N [(S)-omega-amino-2-hydroxyalkyl] kanamycin A derivatives.	1977 Oct	591447

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:30:17 GMT 2023` Edited by `admin` on `Fri Dec 15 16:30:17 GMT 2023`
Record UNII	I61243PDCC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BUTIKACIN

Official Name

English

UK 18892

Code

English

UK 18,892

Code

English

butikacin [INN]

Common Name

English

D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-((S)-4-AMINO-2-HYDROXYBUTYL)-2-DEOXY-

Common Name

English

O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-((S)-4-AMINO-2-HYDROXYBUTYL)-2-DEOXY-D-STREPTAMINE

Common Name

English

UK-18892

Code

English

UK-18,892

Code

English

BUTIKACIN [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2363