SUSALIMOD

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H16N2O5S
Molecular Weight	408.427
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SUSALIMOD

Structure Search

SMILES

CC1=C(NS(=O)(=O)C2=CC=C(C=C2)C#CC3=CC(C(O)=O)=C(O)C=C3)N=CC=C1

InChI

InChIKey=WJLQPSZXCOYTHS-UHFFFAOYSA-N

InChI=1S/C21H16N2O5S/c1-14-3-2-12-22-20(14)23-29(27,28)17-9-6-15(7-10-17)4-5-16-8-11-19(24)18(13-16)21(25)26/h2-3,6-13,24H,1H3,(H,22,23)(H,25,26)

HIDE SMILES / InChI

Molecular Formula	C21H16N2O5S
Molecular Weight	408.427
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/10490905 | https://www.ncbi.nlm.nih.gov/pubmed/10197419 | https://www.ncbi.nlm.nih.gov/pubmed/10522751

Originator

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Tumor necrosis factor 6 Target ID: P06804 Gene ID: 21926.0 Gene Symbol: Tnf Target Organism: Mus musculus (Mouse) Sources: https://www.ncbi.nlm.nih.gov/pubmed/10490905 \| https://adisinsight.springer.com/drugs/800016818	Inhibitor 8297

PubMed

PubMed

Title	Date	PubMed
Pharmacokinetic-pharmacodynamic modeling of the immunomodulating agent susalimod and experimentally induced tumor necrosis factor-alpha levels in the mouse.	1999 Oct	10490905

Patents

Patents

Sample Use Guides

In Vivo Use Guide

mice 25, 50, 100, and 200 mg/kg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:03:03 GMT 2023` Edited by `admin` on `Fri Dec 15 16:03:03 GMT 2023`
Record UNII	I5MPG6F043
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SUSALIMOD

Official Name

English

susalimod [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C308

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

Code System Code Type Description

SMS_ID

100000082969

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

PRIMARY

MESH

C119880

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

PRIMARY

EPA CompTox

DTXSID80164336

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

PRIMARY

NCI_THESAURUS

C74203

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

PRIMARY

ChEMBL

CHEMBL1614646

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

PRIMARY

INN

7347

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

PRIMARY

EVMPD

SUB10785MIG

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

PRIMARY

CAS

149556-49-0

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

PRIMARY

FDA UNII

I5MPG6F043

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

PRIMARY

PUBCHEM

3086668

Created by admin on Fri Dec 15 16:03:03 GMT 2023 , Edited by admin on Fri Dec 15 16:03:03 GMT 2023

PRIMARY

Related Record Type Details


					I5MPG6F043

SUSALIMOD

ACTIVE MOIETY