FONSECIN

COC1=CC(O)=CC2=CC3=C(C(=O)C[C@@](C)(O)O3)C(O)=C12

InChIKey=FKCYENFBFZUSDP-HNNXBMFYSA-N

InChI=1S/C15H14O6/c1-15(19)6-9(17)13-11(21-15)4-7-3-8(16)5-10(20-2)12(7)14(13)18/h3-5,16,18-19H,6H2,1-2H3/t15-/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Condition	Potency
Radical scavenging activity 12 Target ID: CHEMBL613712 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27245874	Activator 1447		0.02 µM [IC50]

PubMed

Title	Date	PubMed
Examination of Potential Exceptions to the F and S Biosynthetic Classification of Fused-Ring Aromatic Polyketides.	2016-12-02	27753463
Induced production of 6,9-dibromoflavasperone, a new radical scavenging naphthopyranone in the marine-mudflat-derived fungus Aspergillus niger.	2016-06	27245874
Aurasperone F--a new member of the naphtho-gamma-pyrone class isolated from a cultured microfungus, Aspergillus niger C-433.	2005-10	16076634

Substance Class	Chemical Created by `admin` on `Tue Apr 01 16:29:16 GMT 2025` Edited by `admin` on `Tue Apr 01 16:29:16 GMT 2025`
Record UNII	I4J4MWF94J
Record Status	`FAILED`
Record Version

Name

Type

Language

TMC-256B1

Preferred Name

English

FONSECIN

Common Name

English

O8-DEMETHYLFONSECIN B

Common Name

English

4H-NAPHTHO(2,3-B)PYRAN-4-ONE, 2,3-DIHYDRO-2,5,8-TRIHYDROXY-6-METHOXY-2-METHYL-

Systematic Name

English

Code System Code Type Description

PUBCHEM

40461268