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Details

Stereochemistry ACHIRAL
Molecular Formula C16H12O7
Molecular Weight 316.2629
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EUPAFOLIN

SMILES

COc1c(cc2c(c(=O)cc(-c3ccc(c(c3)O)O)o2)c1O)O

InChI

InChIKey=FHHSEFRSDKWJKJ-UHFFFAOYSA-N
InChI=1S/C16H12O7/c1-22-16-11(20)6-13-14(15(16)21)10(19)5-12(23-13)7-2-3-8(17)9(18)4-7/h2-6,17-18,20-21H,1H3

HIDE SMILES / InChI

Molecular Formula C16H12O7
Molecular Weight 316.2629
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds.
1994 Aug 3
Application of the electrotopological state index to QSAR analysis of flavone derivatives as HIV-1 integrase inhibitors.
1996 Dec
Flavonoids of Inula britannica protect cultured cortical cells from necrotic cell death induced by glutamate.
2002 Apr 1
A "flavone-polysaccharide" redefined as a mixture of 6-methoxyluteolin penta- and hexa-O-glycosides.
2003 Jul
Iridoids from Globularia dumulosa.
2003 Mar-Apr
Cytotoxic activity of nepetin, a flavonoid from Eupatorium ballotaefolium HBK.
2004 Dec
Effects of natural flavones and flavonols on the kinase activity of Cdk5.
2004 Mar
Topical anti-inflammatory activity of flavonoids and a new xanthone from Santolina insularis.
2005 Jan-Feb
A novel daucosterol derivative and antibacterial activity of compounds from Arctotis arctotoides.
2007 Aug
Anti-inflammatory activity of flavonoids from Eupatorium arnottianum.
2007 Jul 25
Chemical fingerprint and quantitative analysis of Salvia plebeia R.Br. by high-performance liquid chromatography.
2008 Sep 10
Flavonoids and phenolic compounds from Rosmarinus officinalis.
2010 May 12
An unusual dimeric guaianolide with antiprotozoal activity and further sesquiterpene lactones from Eupatoriumperfoliatum.
2011 May
Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy.
2012 Jun
Eupafolin inhibits PGE2 production and COX2 expression in LPS-stimulated human dermal fibroblasts by blocking JNK/AP-1 and Nox2/p47(phox) pathway.
2014 Sep 1
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Jun 26 13:34:56 UTC 2021
Edited
by admin
on Sat Jun 26 13:34:56 UTC 2021
Record UNII
I3O7LF3GED
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EUPAFOLIN
Common Name English
NSC-122416
Code English
NEPETIN
Common Name English
FLAVONE, 3',4',5,7-TETRAHYDROXY-6-METHOXY-
Systematic Name English
4H-1-BENZOPYRAN-4-ONE, 2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-6-METHOXY-
Systematic Name English
5,7,3',4'-TETRAHYDROXY-6-METHOXY FLAVONE
Systematic Name English
6-METHOXYLUTEOLIN
Common Name English
Code System Code Type Description
PUBCHEM
5317284
Created by admin on Sat Jun 26 13:34:56 UTC 2021 , Edited by admin on Sat Jun 26 13:34:56 UTC 2021
PRIMARY
EPA CompTox
520-11-6
Created by admin on Sat Jun 26 13:34:56 UTC 2021 , Edited by admin on Sat Jun 26 13:34:56 UTC 2021
PRIMARY
WIKIPEDIA
NEPETIN
Created by admin on Sat Jun 26 13:34:56 UTC 2021 , Edited by admin on Sat Jun 26 13:34:56 UTC 2021
PRIMARY
FDA UNII
I3O7LF3GED
Created by admin on Sat Jun 26 13:34:56 UTC 2021 , Edited by admin on Sat Jun 26 13:34:56 UTC 2021
PRIMARY
CAS
520-11-6
Created by admin on Sat Jun 26 13:34:56 UTC 2021 , Edited by admin on Sat Jun 26 13:34:56 UTC 2021
PRIMARY
Related Record Type Details
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