EUPAFOLIN

COC1=C(O)C2=C(OC(=CC2=O)C3=CC=C(O)C(O)=C3)C=C1O

InChIKey=FHHSEFRSDKWJKJ-UHFFFAOYSA-N

InChI=1S/C16H12O7/c1-22-16-11(20)6-13-14(15(16)21)10(19)5-12(23-13)7-2-3-8(17)9(18)4-7/h2-6,17-18,20-21H,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds.	1994 Aug 3	7520698
A "flavone-polysaccharide" redefined as a mixture of 6-methoxyluteolin penta- and hexa-O-glycosides.	2003 Jul	12809720
Iridoids from Globularia dumulosa.	2003 Mar-Apr	12710725
Effects of natural flavones and flavonols on the kinase activity of Cdk5.	2004 Mar	15043421
Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy.	2012 Jun	22445328
Eupafolin inhibits PGE2 production and COX2 expression in LPS-stimulated human dermal fibroblasts by blocking JNK/AP-1 and Nox2/p47(phox) pathway.	2014 Sep 1	24967690

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 22:08:30 GMT 2023` Edited by `admin` on `Fri Dec 15 22:08:30 GMT 2023`
Record UNII	I3O7LF3GED
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

EUPAFOLIN

Common Name

English

NSC-122416

Code

English

NEPETIN

Common Name

English

FLAVONE, 3',4',5,7-TETRAHYDROXY-6-METHOXY-

Systematic Name

English

4H-1-BENZOPYRAN-4-ONE, 2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-6-METHOXY-

Systematic Name

English

5,7,3',4'-TETRAHYDROXY-6-METHOXY FLAVONE

Systematic Name

English

6-METHOXYLUTEOLIN

Common Name

English

Code System Code Type Description

PUBCHEM

5317284